{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T08:18:15Z","timestamp":1789460295943,"version":"build-2803163510"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[1998,11,1]],"date-time":"1998-11-01T00:00:00Z","timestamp":909878400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[1998,11]]},"abstract":"<jats:p><jats:bold>Background.<\/jats:bold> Past studies have found inconsistent evidence\n that substance use disorders are related \nto earlier onset of schizophrenia or more severe symptoms. This study examines\n prevalence and \nseverity of current substance use disorders and onset of psychotic illness\n in a multi-facility sample.<\/jats:p><jats:p><jats:bold>Methods.<\/jats:bold> Data are from the Suffolk County Mental Health Project,\n an epidemiological study of \nfirst admission psychosis. The SCID and instruments measuring symptomatology,\n personality and \nbackground characteristics were administered. Respondents were stratified\n into three groups: (<jats:italic>a<\/jats:italic>) no \nlife-time substance diagnosis; (<jats:italic>b<\/jats:italic>) in remission or reporting current\n mild use at admission; and (<jats:italic>c<\/jats:italic>) \ncurrent moderate\u2013severe substance abuse at admission.<\/jats:p><jats:p><jats:bold>Results.<\/jats:bold> Using the SCID severity rating, 17\u00b74% of males\n and 6\u00b72% of the females had moderate or \nsevere current substance abuse, while 41\u00b75% of males and 68\u00b72%\n of females had no lifetime \nsubstance diagnosis. In almost all cases categorized as moderate\u2013severe,\n the substance diagnosis \npredated onset of psychosis. Females categorized as moderate\u2013severe\n had an earlier age of onset of \npsychosis than did females in the other groups. There were only slight\n differences in symptom \nseverity among the groups but more marked antisocial behaviour in the moderate\u2013severe\n group. \nVariables discriminating the moderate\u2013severe from non-abuse groups\n were BPRS thought \ndisturbance, adult anti-social behaviour and current cigarette smoking\n for males and adult antisocial \nbehaviour and child\u2013teen antisocial behaviour for females.<\/jats:p><jats:p><jats:bold>Conclusions.<\/jats:bold> Severity of substance abuse does not appear to\n be a pivotal correlate of the early \nfeatures of psychotic illness.<\/jats:p>","DOI":"10.1017\/s0033291798007399","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:33:33Z","timestamp":1027762413000},"page":"1411-1419","source":"Crossref","is-referenced-by-count":113,"title":["Prevalence and severity of substance use disorders \nand onset of psychosis in first-admission psychotic patients"],"prefix":"10.1017","volume":"28","author":[{"given":"J.","family":"RABINOWITZ","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. J.","family":"BROMET","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"LAVELLE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"CARLSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"KOVASZNAY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. E.","family":"SCHWARTZ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[1998,11,1]]},"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291798007399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T15:57:49Z","timestamp":1557503869000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291798007399\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,11]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,11]]}},"alternative-id":["S0033291798007399"],"URL":"https:\/\/doi.org\/10.1017\/s0033291798007399","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,11]]}}}