{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T18:49:30Z","timestamp":1761418170169},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[1999,7,1]],"date-time":"1999-07-01T00:00:00Z","timestamp":930787200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[1999,7]]},"abstract":"<jats:p><jats:bold>Background.<\/jats:bold> Depression, anxiety and fatigue are among the most common symptoms presented in \nprimary care. Whether such symptoms indicate discrete psychological syndromes or whether they \nresult from a common vulnerability is not clear. This study examined longitudinally the patterns of \nco-morbidity between prolonged fatigue and other forms of psychological distress in patients \nattending general practitioners.<\/jats:p><jats:p><jats:bold>Methods.<\/jats:bold> Adults attending primary care completed questionnaires designed to detect cases of \nprolonged fatigue and psychological distress at presentation and 12 months later.<\/jats:p><jats:p><jats:bold>Results.<\/jats:bold> Of 652 patients, the prevalence rates of \u2018prolonged fatigue\u2019 alone, \u2018psychological distress\u2019 \nalone, \u2018prolonged fatigue+psychological distress\u2019 and \u2018no disorder\u2019 were 7%, 19%, 15% and \n59% respectively at initial assessment. Of those patients with any prolonged fatigue syndrome \ninitially, 58% still reported fatigue 12 months later (representing 13% of the total sample). Most \nimportantly, the risk of developing prolonged fatigue was not increased in patients who initially had \npsychological distress (OR = 0\u00b795; 95% CI 0\u00b72\u20133\u00b76), neither was the risk of developing psychological \ndistress increased in patients who initially had prolonged fatigue (OR = 1\u00b74; 95% CI 0\u00b76\u20133\u00b74).<\/jats:p><jats:p><jats:bold>Conclusions.<\/jats:bold> This study indicates that prolonged fatigue is a persistent diagnosis over time. The \nlongitudinal patterns of co-morbidity with psychological distress do not support an aetiological \nmodel that proposes a common vulnerability factor for these disorders. Psychiatric classification \nsystems may be better served by treating prolonged fatigue and psychological distress as \nindependent disorders.<\/jats:p>","DOI":"10.1017\/s0033291799008582","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:33:33Z","timestamp":1027762413000},"page":"855-861","source":"Crossref","is-referenced-by-count":66,"title":["The temporal stability and co-morbidity of prolonged \nfatigue: a longitudinal study in primary care"],"prefix":"10.1017","volume":"29","author":[{"given":"I.","family":"HICKIE","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"KOSCHERA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"HADZI-PAVLOVIC","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"BENNETT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"LLOYD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1999,7,1]]},"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291799008582","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T17:44:48Z","timestamp":1555004688000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291799008582\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,7]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1999,7]]}},"alternative-id":["S0033291799008582"],"URL":"https:\/\/doi.org\/10.1017\/s0033291799008582","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,7]]}}}