{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:39:45Z","timestamp":1760132385833},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":11019,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control"],"published-print":{"date-parts":[[1984,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the neonatal intensive care unit (NICU) of one hospital, 16 infants became colonized or infected with multiply-resistant<jats:italic>Escherichia coli<\/jats:italic>(MR-<jats:italic>E.coli<\/jats:italic>) over an 8-month period. Isolates were obtained from blood, urine, and sputum of three patients and from rectal surveillance cultures of 13 patients. The one patient with the blood isolate died. A matched case-control study identified continuous feeding (nine of 16 cases vs. one of 16 controls, p \u2264 0.001) and receipt of aminoglycosides (p \u2264 0.03) as risk factors. For case-babies not exposed to continuous feeding, duration of bolus feeding was significantly greater than for their controls (cases, 22 days; controls, 7 days; p \u2264 0.02). All 16 isolates were the same serotype and were resistant to amikacin, tobramycin, kanamycin, and gentamicin. The epidemiologic investigation suggested that MR-<jats:italic>E. coli<\/jats:italic>may have spread from person-to-person on the hands of personnel and that MR-<jats:italic>E. coli<\/jats:italic>persisted in the NICU for 8 months until effective control measures were instituted.<\/jats:p>","DOI":"10.1017\/s0195941700061038","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T04:53:58Z","timestamp":1470200038000},"page":"519-524","source":"Crossref","is-referenced-by-count":9,"title":["A Nursery Outbreak of Multiple-Aminoglycoside-Resistant<i>Escherichia coli<\/i>"],"prefix":"10.1017","volume":"5","author":[{"given":"Robert R","family":"Gaynes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally A.","family":"Reeves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Noble","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clyde","family":"Thornsberry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Culver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James R.","family":"Allen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William J.","family":"Martone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700061038_ref006","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03330100037027"},{"key":"S0195941700061038_ref007","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/8.suppl_A.89"},{"key":"S0195941700061038_ref001","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/5.Supplement_2.S212"},{"key":"S0195941700061038_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(81)90782-8"},{"key":"S0195941700061038_ref002","volume-title":"Diagnostic Procedures for Bacterial, Mycotic and Parasitic Infections","author":"Balows","year":"1981"},{"key":"S0195941700061038_ref003","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/141.3.338"},{"key":"S0195941700061038_ref009","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0002-9343(81)80001-0","article-title":"Strategies for prevention and control of multiple drug-resistant nosocomial infection","volume":"70","author":"Weinstein","year":"1981","journal-title":"Am J Med"},{"key":"S0195941700061038_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90654-4"},{"key":"S0195941700061038_ref005","doi-asserted-by":"publisher","DOI":"10.1017\/S0195941700057829"}],"container-title":["Infection Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0195941700061038","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T20:23:45Z","timestamp":1656966225000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0195941700061038\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,11]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1984,11]]}},"alternative-id":["S0195941700061038"],"URL":"https:\/\/doi.org\/10.1017\/s0195941700061038","relation":{},"ISSN":["0195-9417","2327-9451"],"issn-type":[{"value":"0195-9417","type":"print"},{"value":"2327-9451","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,11]]}}}