{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,25]],"date-time":"2024-08-25T01:16:13Z","timestamp":1724548573694},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T00:00:00Z","timestamp":1182211200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Technol Assess Health Care"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p><jats:bold>Objectives:<\/jats:bold>The aim of this study was to evaluate the cost-effectiveness of on-site automated external defibrillators (AEDs) in the initial management of cardiac arrest in Ontario.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold>This was a cost-effectiveness analysis based on published literature and data from the Canadian Institute of Health Information. The participants were fictitious male and female cardiac arrest patients who were initially managed with on-site AEDs, compared with similar patients managed without on-site AEDs. This group included a subgroup of high-risk patients (i.e., heart failure and left ventricular ejection fraction &lt;35 percent). The analysis was conducted in a variety of settings including hospitals and homes in Ontario, Canada. The main outcome evaluated was cost per quality-adjusted life-year (QALY) gained from a payer's perspective.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>Cost per QALY (all costs reported in Canadian dollars) was $12,768 when AEDs were deployed in hospitals, $511,766 when deployed in office buildings, $2,360,023 when deployed in apartment buildings, $87,569 when deployed in homes of high-risk patients, and $1,529,371 when deployed in homes of people older than 55 years of age.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold>Indiscriminate deployment of AEDs is not a cost-effective means of improving health outcomes of cardiac arrest. Their use should be restricted to emergency response programs, high-risk sites (such as hospitals), and high-risk patients.<\/jats:p>","DOI":"10.1017\/s0266462307070523","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T08:39:23Z","timestamp":1182415163000},"page":"362-367","source":"Crossref","is-referenced-by-count":8,"title":["Assessing automated external defibrillators in preventing deaths from sudden cardiac arrest: An economic evaluation"],"prefix":"10.1017","volume":"23","author":[{"given":"Waseem","family":"Sharieff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kellee","family":"Kaulback","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,19]]},"reference":[{"key":"S0266462307070523_ref012","doi-asserted-by":"crossref","unstructured":"Nichol G , Valenzuela T , Roe D , et al.2003 Cost effectiveness of defibrillation by targeted responders in public settings.Circulation. 108:697\u2013703.","DOI":"10.1161\/01.CIR.0000084545.65645.28"},{"key":"S0266462307070523_ref017","doi-asserted-by":"crossref","unstructured":"Stiell IG , Wells GA , Spaite DW , et al.1998 The Ontario Prehospital Advanced Life Support (OPALS) Study: Rationale and methodology for cardiac arrest patients.Ann Emerg Med. 32:180\u2013190.","DOI":"10.1016\/S0196-0644(98)70135-0"},{"key":"S0266462307070523_ref014","unstructured":"Statistics Canada. Tables by province or territory: Ontario. Available at: http:\/\/www40.statcan.ca\/l01\/pro01\/pro106.htm. Accessed 21 July 2006."},{"key":"S0266462307070523_ref016","doi-asserted-by":"crossref","unstructured":"Stiell IG , Wells GA , Field BJ , et al.1999 Improved out-of-hospital cardiac arrest survival through the inexpensive optimization of an existing defibrillation program: OPALS study phase II. Ontario Prehospital Advanced Life Support.JAMA. 281:1175\u20131181.","DOI":"10.1001\/jama.281.13.1175"},{"key":"S0266462307070523_ref009","doi-asserted-by":"crossref","unstructured":"Mancini ME , Kaye W .1998 In-hospital first-responder automated external defibrillation: What critical care practitioners need to know.Am J Crit Care. 7:314\u2013319.","DOI":"10.4037\/ajcc1998.7.4.314"},{"key":"S0266462307070523_ref008","doi-asserted-by":"crossref","unstructured":"Larsen MP , Eisenberg MS , Cummins RO , et al.1993 Predicting survival from out-of-hospital cardiac arrest: A graphic model.Ann Emerg Med. 22:1652\u20131658.","DOI":"10.1016\/S0196-0644(05)81302-2"},{"key":"S0266462307070523_ref001","doi-asserted-by":"crossref","unstructured":"American Heart Association 2005 Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.2005 Part 5. Electrical therapies. 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A prospective study.Acad Emerg Med. 6:95\u2013102.","DOI":"10.1111\/j.1553-2712.1999.tb01044.x"},{"key":"S0266462307070523_ref015","doi-asserted-by":"crossref","unstructured":"Stiell IG , Wells GA , De Maio VJ , et al.1999 Modifiable factors associated with improved cardiac arrest survival in a multicenter basic life support\/defibrillation system: OPALS Study Phase I results. Ontario Prehospital Advanced Life Support.Ann Emerg Med. 33:44\u201350.","DOI":"10.1016\/S0196-0644(99)70415-4"},{"key":"S0266462307070523_ref003","doi-asserted-by":"crossref","unstructured":"Bardy GH , Lee KL , Mark DB , et al.2005 Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure.N Engl J Med. 352:225\u2013237.","DOI":"10.1056\/NEJMoa043399"},{"key":"S0266462307070523_ref018","unstructured":"Vaillancourt C , Stiell IG , Canadian Cardiovascular Outcomes Research Team .2004 Cardiac arrest care and emergency medical services in Canada.Can J Cardiol. 20:1081\u20131090."},{"key":"S0266462307070523_ref005","doi-asserted-by":"crossref","unstructured":"Cram P , Vijan S , Katz D , et al.2005 Cost-effectiveness of in-home automated external defibrillators for individuals at increased risk of sudden cardiac death: There's no place like home?J Gen Intern Med. 20:251\u2013258.","DOI":"10.1111\/j.1525-1497.2005.40247.x"},{"key":"S0266462307070523_ref013","unstructured":"Simpson CS , O'Neill BJ , Sholdice MM , et al.2005 Canadian Cardiovascular Society commentary on implantable cardioverter defibrillators in Canada: Waiting times and access to care issues.Can J Cardiol. 21:19\u201324."}],"container-title":["International Journal of Technology Assessment in Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0266462307070523","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T05:26:32Z","timestamp":1707974792000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0266462307070523\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,19]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["S0266462307070523"],"URL":"https:\/\/doi.org\/10.1017\/s0266462307070523","relation":{},"ISSN":["0266-4623","1471-6348"],"issn-type":[{"value":"0266-4623","type":"print"},{"value":"1471-6348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,19]]}}}