{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:41:52Z","timestamp":1785426112922,"version":"3.56.0"},"reference-count":8,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"unspecified","delay-in-days":344,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["AID-121-C-17-00004"],"award-info":[{"award-number":["AID-121-C-17-00004"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Technol Assess Health Care"],"published-print":{"date-parts":[[2025]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n Health technology assessment (HTA) has become an integral part of Ukraine\u2019s health system since its formal introduction into national legislation in 2017. By 2020, HTA was mandated for evaluating publicly funded medicines, laying the groundwork for more evidence-based healthcare decisions. Although the creation of an independent HTA agency was initially planned for 2022, implementation was delayed due to the COVID-19 pandemic and Russia\u2019s ongoing invasion. The relevant Cabinet Resolution calls for the establishment of an autonomous agency by January 2026. This commentary outlines a strategic, evidence-informed framework to guide the agency\u2019s formation.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Drawing on the 2018 State Strategy for Access to Medicines, the 2022 Law on Medicinal Products, and international best practices, we proposed to the Government of Ukraine a two-tier structure encompassing\n core business<\/jats:italic>\n functions (HTA and appraisal, guideline development, pricing, and listing) and\n support business<\/jats:italic>\n functions (data and analytics, finance and strategy, IT, human resources, legal, and communications). Each department is tasked with clear mandates and supported by performance indicators to promote transparency, accountability, and operational efficiency.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A phased roadmap for 2025\u20132027 details the legal, institutional, and financial steps required for successful implementation. Key opportunities \u2013 including international partnerships and system-wide reform \u2013 are weighed alongside risks such as funding uncertainty, workforce limitations, and geopolitical instability.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n By embedding HTA into national policy processes and ensuring institutional independence, Ukraine can enhance the value of healthcare investments and build long-term resilience into its health system.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/s0266462325103255","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T06:30:36Z","timestamp":1765434636000},"source":"Crossref","is-referenced-by-count":0,"title":["Establishing an independent HTA agency in Ukraine: a conceptual framework for governance, operations, and long-term sustainability"],"prefix":"10.1017","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8388-0179","authenticated-orcid":false,"given":"Rabia","family":"Sucu","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wf4pt88","id-type":"ROR","asserted-by":"publisher"}],"name":"Management Sciences for Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Erku","sequence":"additional","affiliation":[{"name":"Economic, Policy and Innovation Centre (EPIC) for Health Systems"},{"id":[{"id":"https:\/\/ror.org\/02sc3r913","id-type":"ROR","asserted-by":"publisher"}],"name":"Griffith University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olena","family":"Filiniuk","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wf4pt88","id-type":"ROR","asserted-by":"publisher"}],"name":"SAFEMed, Management Sciences for Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Kohler","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wf4pt88","id-type":"ROR","asserted-by":"publisher"}],"name":"SAFEMed, Management Sciences for Health"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"S0266462325103255_r3","unstructured":"3. Law of Ukraine. \u201cOn Medicinal Products\u201d (No. 2469-IX). 2022. Available from: https:\/\/zakon.rada.gov.ua\/laws\/show\/en\/2469-20?lang=uk#Text."},{"key":"S0266462325103255_r1","unstructured":"1. Law of Ukraine. \u201cOn State Financial Guarantees of Medical Service to the Population.\u201d\u00a0No. 2168-VIII. 2017. Available from: https:\/\/zakon.rada.gov.ua\/laws\/show\/2168-19#Text."},{"key":"S0266462325103255_r6","unstructured":"6. Cabinet of Ministers of Ukraine Resolution No. 1022 . \u201cOn Approval of the State Strategy for Implementing State Policy on Providing Medicines to the Population Until 2025.\u201d December 5, 2018. Available from:\u00a0https:\/\/zakon.rada.gov.ua\/laws\/show\/1022-2018-%D0%BF?lang=en#Text."},{"key":"S0266462325103255_r5","unstructured":"5. Law of Ukraine. \u201cFundamentals of the Legislation of Ukraine on Healthcare\u201d No. 2801-XII. Revised March 27, 2025. Available from:\u00a0https:\/\/zakon.rada.gov.ua\/laws\/show\/en\/2801-12\/ed20250327#Text."},{"key":"S0266462325103255_r2","unstructured":"2. Cabinet of Ministers of Ukraine Resolution No. 1300. December 23, 2020. Available from: https:\/\/zakon.rada.gov.ua\/laws\/show\/1300-2020-%D0%BF#Text."},{"key":"S0266462325103255_r7","volume-title":"Mapping of HTA national organisations, programmes and processes in EU and Norway","author":"Chamova","year":"2017"},{"key":"S0266462325103255_r8","unstructured":"8. Wilsdon, T , Serota, A . A Comparative Analysis of the Role and Impact of HTA. 2011. Available from: https:\/\/www.efpia.eu\/media\/25695\/a-comparative-analysis-of-the-role-and-impact-of-health-technology-assessment-2011.pdf."},{"key":"S0266462325103255_r4","unstructured":"4. Council Directive 89\/105\/EEC. Transparency of Measures Regulating the Prices of Medicinal Products for Human Use and their Inclusion in the Scope of National Health Insurance Systems. 21 December 1988. Available from: https:\/\/eur-lex.europa.eu\/EN\/legal-content\/summary\/transparency-of-decisions-regulating-the-prices-and-reimbursement-of-medicinal-products-in-european-union-member-states.html#:~:text=It%20aims%20to%20ensure%20that,to%20the%20EU%20pharmaceutical%20trade."}],"container-title":["International Journal of Technology Assessment in Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0266462325103255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T06:30:38Z","timestamp":1765434638000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0266462325103255\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025]]}},"alternative-id":["S0266462325103255"],"URL":"https:\/\/doi.org\/10.1017\/s0266462325103255","relation":{},"ISSN":["0266-4623","1471-6348"],"issn-type":[{"value":"0266-4623","type":"print"},{"value":"1471-6348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e85"}}