{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T08:40:42Z","timestamp":1785400842065,"version":"3.56.0"},"reference-count":54,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"unspecified","delay-in-days":88,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Technol Assess Health Care"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    With the ongoing discussion around the implementation of low-dose computed tomography (LDCT) screening for lung cancer, increasing numbers of model-based economic evaluations have been conducted. We systematically reviewed the published literature for economic evaluations of LDCT screening for lung cancer in people at high risk, updating this review in 2024. We identified a total of 57 economic evaluations; two-thirds of which developed\n                    <jats:italic>de novo<\/jats:italic>\n                    decision-analytic models. In our most recent update, of the 22 economic evaluations identified, only one used a model published before 2021. There may be advantages to developing new models, but the huge possibility of research waste cannot be ignored. Better quality of reporting (both in terms of clarity and completeness), improving the availability of existing models, and comparative analysis of different models can help to advance modeling methods in areas of complexity, such as screening for cancer. Ultimately, this should lead to policy decisions based on the best available evidence.\n                  <\/jats:p>","DOI":"10.1017\/s0266462326103687","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:26:53Z","timestamp":1774866413000},"source":"Crossref","is-referenced-by-count":0,"title":["Considering research waste in economic evaluations of low-dose computed tomography screening for lung cancer"],"prefix":"10.1017","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1778-3518","authenticated-orcid":false,"given":"Jaime L.","family":"Peters","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03yghzc09","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Exeter"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan","family":"Snowsill","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03yghzc09","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Exeter"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Robinson","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03yghzc09","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Exeter"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Griffin","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03yghzc09","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Exeter"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7349-0616","authenticated-orcid":false,"given":"Christopher","family":"Hyde","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03yghzc09","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Exeter"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"S0266462326103687_r25","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31822e59b3"},{"key":"S0266462326103687_r12","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2024.2404359"},{"key":"S0266462326103687_r16","doi-asserted-by":"publisher","DOI":"10.3310\/hta20400"},{"key":"S0266462326103687_r29","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34746"},{"key":"S0266462326103687_r41","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.2472"},{"key":"S0266462326103687_r36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2025.01.007"},{"key":"S0266462326103687_r22","doi-asserted-by":"publisher","DOI":"10.7326\/M19-0322"},{"key":"S0266462326103687_r9","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-023-11800-7"},{"key":"S0266462326103687_r11","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-021-01422-w"},{"key":"S0266462326103687_r46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2020.05.004"},{"key":"S0266462326103687_r8","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15184445"},{"key":"S0266462326103687_r21","unstructured":"21. National Cancer Institute Cancer Intervention and Surveillance Modeling Network (CISNET). Lung cancer outcomes simulator. Available from: https:\/\/resources.cisnet.cancer.gov\/registry\/packages\/lcos-stanford\/ (accessed 28 September 2020)."},{"key":"S0266462326103687_r14","unstructured":"14. Lung Cancer Policy Network. Interactive map of lung cancer screening. 2024. Available from: https:\/\/www.lungcancerpolicynetwork.com\/interactive-map-of-lung-cancer-screening\/ (accessed 10 December)."},{"key":"S0266462326103687_r7","doi-asserted-by":"publisher","DOI":"10.14740\/wjon1882"},{"key":"S0266462326103687_r30","unstructured":"30. National Cancer Institute Cancer Intervention and Surveillance Modeling Network (CISNET). University of michigan lung cancer screening model. Available from: https:\/\/resources.cisnet.cancer.gov\/registry\/packages\/um-lcsc-michigan\/ (accessed 28 September 2020)."},{"key":"S0266462326103687_r32","doi-asserted-by":"publisher","DOI":"10.57264\/cer-2024-0102"},{"key":"S0266462326103687_r24","unstructured":"24. National Cancer Institute Cancer Intervention and Surveillance Modeling Network (CISNET). Lung cancer policy model. Available from: https:\/\/resources.cisnet.cancer.gov\/registry\/packages\/lcpm-mgh\/ (accessed 28 September 2020)."},{"key":"S0266462326103687_r20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071379"},{"key":"S0266462326103687_r10","doi-asserted-by":"publisher","DOI":"10.1016\/j.vhri.2022.10.002"},{"key":"S0266462326103687_r43","doi-asserted-by":"publisher","DOI":"10.1007\/s41669-022-00346-2"},{"key":"S0266462326103687_r17","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2018.10.029"},{"key":"S0266462326103687_r48","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2021.10.008"},{"key":"S0266462326103687_r45","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12241"},{"key":"S0266462326103687_r49","doi-asserted-by":"publisher","DOI":"10.1002\/hec.1148"},{"key":"S0266462326103687_r31","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2023.2288739"},{"key":"S0266462326103687_r6","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2021.480"},{"key":"S0266462326103687_r54","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2020.12.013"},{"key":"S0266462326103687_r1","doi-asserted-by":"publisher","DOI":"10.1186\/s41512-023-00162-0"},{"key":"S0266462326103687_r34","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2022.104319"},{"key":"S0266462326103687_r23","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkz035"},{"key":"S0266462326103687_r4","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-5002(00)00239-7"},{"key":"S0266462326103687_r3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2021.11.1352"},{"key":"S0266462326103687_r5","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(01)00205-2"},{"key":"S0266462326103687_r38","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-022-02026-8"},{"key":"S0266462326103687_r40","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1312547"},{"key":"S0266462326103687_r18","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2011.0814"},{"key":"S0266462326103687_r50","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-200826020-00004"},{"key":"S0266462326103687_r27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002225"},{"key":"S0266462326103687_r35","doi-asserted-by":"publisher","DOI":"10.2196\/36425"},{"key":"S0266462326103687_r53","unstructured":"53. Health Technology Assessment Policy and Methods Review Reference Committee. Accelerating access to the best medicines for Australians now into the future: A review of Australia\u2019s health technology assessment policies and methods for the Australian Government. 2024. https:\/\/www.health.gov.au\/sites\/default\/files\/2024-09\/health-technology-assessment-policy-and-methods-review-final-report_0.pdf"},{"key":"S0266462326103687_r42","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2016.09.013"},{"key":"S0266462326103687_r26","unstructured":"26. National Cancer Institute Cancer Intervention and Surveillance Modeling Network (CISNET). MISCAN-lung. 2020. Available from: https:\/\/resources.cisnet.cancer.gov\/registry\/packages\/miscan-lung-erasmus\/ (accessed 28 September 2020)."},{"key":"S0266462326103687_r51","doi-asserted-by":"publisher","DOI":"10.7326\/M16-0161"},{"key":"S0266462326103687_r47","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0000000000000700"},{"key":"S0266462326103687_r28","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2018.05.008"},{"key":"S0266462326103687_r39","doi-asserted-by":"publisher","DOI":"10.7326\/M17-1401"},{"key":"S0266462326103687_r19","first-page":"272","article-title":"Offering lung cancer screening to high-risk medicare beneficiaries saves lives and is cost-effective: an actuarial analysis","volume":"7","author":"Pyenson","year":"2014","journal-title":"Am Health Drug Benefits"},{"key":"S0266462326103687_r15","doi-asserted-by":"publisher","DOI":"10.1186\/1478-7547-6-5"},{"key":"S0266462326103687_r52","unstructured":"52. National Institute for Health and Care Excellence (NICE). Use of disease-specific reference models in economic evaluations: NICE position statement (ECD18). 2025. https:\/\/www.nice.org.uk\/corporate\/ecd18"},{"key":"S0266462326103687_r33","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-21-0155"},{"key":"S0266462326103687_r44","doi-asserted-by":"publisher","DOI":"10.1007\/s40258-022-00743-y"},{"key":"S0266462326103687_r2","doi-asserted-by":"publisher","DOI":"10.3310\/hta22690"},{"key":"S0266462326103687_r37","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djz164"},{"key":"S0266462326103687_r13","article-title":"Shall we screen lung cancer with volume computed tomography in Austria? A cost-effectiveness modelling study","volume":"16","author":"ten Berge","year":"2024","journal-title":"Cancer"}],"container-title":["International Journal of Technology Assessment in Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0266462326103687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T07:03:25Z","timestamp":1784271805000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0266462326103687\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":54,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026]]}},"alternative-id":["S0266462326103687"],"URL":"https:\/\/doi.org\/10.1017\/s0266462326103687","relation":{},"ISSN":["0266-4623","1471-6348"],"issn-type":[{"value":"0266-4623","type":"print"},{"value":"1471-6348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e45"}}