{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T22:13:05Z","timestamp":1773180785135,"version":"3.50.1"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"unspecified","delay-in-days":3410,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title><jats:sec id=\"S0317167100004273_abs1\"><jats:title>Background:<\/jats:title><jats:p>Acute neurological deterioration secondary to cervical disc herniation not related to external trauma is very rare, with only six published reports to date. In most cases, acute symptoms were due to progression of disc herniation in the presence of pre-existing spinal canal stenosis.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100004273_abs2\"><jats:title>Case report:<\/jats:title><jats:p>A 42-year-old man developed weakness and numbness in his arms and legs immediately following a sneeze. On physical examination he had upper motor neuron signs that progressed over a few hours to a complete C5 quadriplegia. An emergent magnetic resonance imaging study revealed a massive C4\/5 disc herniation. He underwent emergency anterior cervical discectomy and fusion. Postoperatively, the patient remained quadriplegic. Eighteen days later, while receiving rehabilitation therapy, he expired secondary to a pulmonary embolus. Autopsy confirmed complete surgical decompression of the spinal cord.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100004273_abs3\"><jats:title>Conclusions:<\/jats:title><jats:p>Our case demonstrates that acute quadriplegia secondary to cervical disc herniation may occur without a history of myelopathy or spinal canal stenosis after an event as benign as a sneeze.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0317167100004273","type":"journal-article","created":{"date-parts":[[2014,12,12]],"date-time":"2014-12-12T15:33:09Z","timestamp":1418398389000},"page":"356-358","source":"Crossref","is-referenced-by-count":11,"title":["Sudden Quadriplegia after Acute Cervical Disc Herniation"],"prefix":"10.1017","volume":"32","author":[{"given":"Venkatraman","family":"Sadanand","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Varughese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daryl R.","family":"Fourney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,12,2]]},"reference":[{"key":"S0317167100004273_ref012","first-page":"427","article-title":"Nontraumatic acuteparaplegia associated with cervical disc herniation: a case report","volume":"213","author":"Uyema","year":"1999","journal-title":"Surg Neurol"},{"key":"S0317167100004273_ref009","first-page":"1395","article-title":"Acute paraplegia due tocervical disc herniation: a case report","volume":"26","author":"Kawaguchi","year":"1991","journal-title":"Rinsho Seikei Geka"},{"key":"S0317167100004273_ref006","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2002.29621"},{"key":"S0317167100004273_ref013","first-page":"741","article-title":"Progressive myelopathy causedby multiple cervical disc herniation: a report of two cases","volume":"46","author":"Warabi","year":"1995","journal-title":"Rinsho Seikei Geka"},{"key":"S0317167100004273_ref008","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1973.03230030022005"},{"key":"S0317167100004273_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0735-6757(91)90213-4"},{"key":"S0317167100004273_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100052628"},{"key":"S0317167100004273_ref007","doi-asserted-by":"publisher","DOI":"10.1007\/s003810000268"},{"key":"S0317167100004273_ref002","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.7.1115"},{"key":"S0317167100004273_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(85)80647-8"},{"key":"S0317167100004273_ref011","article-title":"Nontraumatic acute completeparaplegia resulting from cervical disc herniation: a case report","volume":"15","author":"Suzuki","year":"2003","journal-title":"Spine"},{"key":"S0317167100004273_ref001","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199009000-00027"},{"key":"S0317167100004273_ref010","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1982.57.2.0278"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167100004273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T07:14:05Z","timestamp":1554966845000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167100004273\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["S0317167100004273"],"URL":"https:\/\/doi.org\/10.1017\/s0317167100004273","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}