{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T12:15:01Z","timestamp":1790943301146,"version":"4.1.0"},"reference-count":47,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"unspecified","delay-in-days":3502,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title><jats:sec id=\"S0317167100004492_abs1\"><jats:title>Objective:<\/jats:title><jats:p>Our goal was to perform a quantitative evaluation of the improvement in functional capacity, quality of life, mental function, reduction in drug intake and impact on hospital admissions after vertebroplasty in the treatment of osteoporotic compression fractures. The efficacy of vertebroplasty in relief of pain has been addressed in previous publications but the quantitative evaluation of improvement in quality of life has not been addressed before.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100004492_abs2\"><jats:title>Methods:<\/jats:title><jats:p>This is a prospective study of 42 patients with 83 symptomatic vertebral fractures treated by vertebroplasty with a mean follow-up of 9.1 months. The outcome was measured by pre and postoperatively utilizing the Visual Analogue Scale, the Oswestry Disability Index, the Rolland Morris Scale for Back Pain and EuroQol-5D questionnaire (EQ-5D). The postoperative evaluations were performed at one week, one month, three month, and six month intervals thereafter.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100004492_abs3\"><jats:title>Results:<\/jats:title><jats:p>In 34 out of 39 active patients, marked pain relief was noted (87%). The Visual Analogue Scale score improved from a mean preoperative score of 8.2 to a mean postoperative score of 2.9 (p=0.0000003) at one week follow up and 3.9 at the last follow-up. The Rolland Morris Scale for Back Pain showed a drop from a mean preoperative rating of 13 to a mean postoperative rating of 10, showing a 25% improvement (p= 0.0207). The Oswestry Disability Index preoperatively was 64.4 which improved to 43.8 postoperatively, showing a 32% improvement (p= 0.0207). The EQ-5D showed a mean preoperative index value of 0.097 and mean postoperative index value of 0.592 (p = 0.0000003). All p-values were determined by the Willcoxin sign-ranked test.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100004492_abs4\"><jats:title>Conclusion:<\/jats:title><jats:p>Vertebroplasty is a safe and efficacious procedure with a resulting improvement in pain and quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0317167100004492","type":"journal-article","created":{"date-parts":[[2014,12,12]],"date-time":"2014-12-12T10:30:34Z","timestamp":1418380234000},"page":"487-495","source":"Crossref","is-referenced-by-count":34,"title":["Vertebroplasty in Osteoporotic Spine Fractures: A Quality of Life Assessment"],"prefix":"10.1017","volume":"32","author":[{"given":"Krishna","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.K.","family":"Verma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jefferson","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alika","family":"LaFontaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2014,12,2]]},"reference":[{"key":"S0317167100004492_ref011","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.200.2.8685351"},{"key":"S0317167100004492_ref044","first-page":"114","article-title":"Comparing kyphoplasty and vertebroplasty","volume":"1","author":"Truumees","year":"2002","journal-title":"Advances in osteoporotic fracture management"},{"key":"S0317167100004492_ref042","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200107150-00002"},{"key":"S0317167100004492_ref035","first-page":"1807","article-title":"Value of Bone Scan imaging in predicting pain relief from percutaneous vertebroplasty in osteoporotic vertebral fractures","volume":"21","author":"Maynard","year":"2000","journal-title":"AJNR"},{"key":"S0317167100004492_ref030","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200211002-00014"},{"key":"S0317167100004492_ref036","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199909010-00004"},{"key":"S0317167100004492_ref023","first-page":"373","article-title":"PercutaneousVertebroplasty: A developing standard in of care for vertebralcompression fractures","volume":"22","author":"Mathis","year":"2001","journal-title":"AJNR"},{"key":"S0317167100004492_ref032","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199908010-00004"},{"key":"S0317167100004492_ref002","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1997.12.1.24"},{"key":"S0317167100004492_ref029","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200310000-00024"},{"key":"S0317167100004492_ref043","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000085092.84097.7B"},{"key":"S0317167100004492_ref004","first-page":"372","article-title":"Percutaneous injectionof methylmethacrylate in the vertebral body for t treatment of various diseases; 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