{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:36:46Z","timestamp":1776706606491,"version":"3.51.2"},"reference-count":8,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"unspecified","delay-in-days":3226,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title>\n\t  <jats:sec id=\"S0317167100004790_abs1\">\n\t    <jats:title>Background:<\/jats:title>\n\t    <jats:p>Non-invasive mechanical ventilation (BiPAP) has been introduced for use in neuromuscular respiratory disease such as amyotrophic lateral sclerosis and myasthenia gravis. There is no experience in Guillain-Barr\u00e9 syndrome.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0317167100004790_abs2\">\n\t    <jats:title>Methods:<\/jats:title>\n\t    <jats:p>We describe for the first time the use of BiPAP to assist in the work of breathing in two consecutive patients with progressing Guillain-Barr\u00e9 syndrome (GBS) and marginal pulmonary function.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0317167100004790_abs3\">\n\t    <jats:title>Results:<\/jats:title>\n\t    <jats:p>Our initial attempts to use BiPAP in GBS and early neuromuscular respiratory failure were totally unsuccessful. There was marked initial improvement; however, emergency intubation was needed in both patients, one of which became acutely cyanotic.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0317167100004790_abs4\">\n\t    <jats:title>Conclusions:<\/jats:title>\n\t    <jats:p>Until more experience is available, we strongly warn against using BiPAP in deteriorating patients with GBS.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/s0317167100004790","type":"journal-article","created":{"date-parts":[[2014,12,12]],"date-time":"2014-12-12T15:30:25Z","timestamp":1418398225000},"page":"105-106","source":"Crossref","is-referenced-by-count":32,"title":["BiPAP in Early Guillain-Barr\u00e9 Syndrome May Fail"],"prefix":"10.1017","volume":"33","author":[{"given":"Eelco F.M.","family":"Wijdicks","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuhin K.","family":"Roy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,12,2]]},"reference":[{"key":"S0317167100004790_manual_ref-2","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/BF03256662","article-title":"BiPAP ventilation as assistancefor patients presenting with respiratory distress in the department of emergency medicine","volume":"2","author":"Yosefy","year":"2003","journal-title":"Am J Respir Med"},{"key":"S0317167100004790_manual_ref-9","doi-asserted-by":"publisher","DOI":"10.1378\/chest.116.1.166"},{"key":"S0317167100004790_manual_ref-5","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/bja\/aeg252","article-title":"Non-invasive ventilation toavoid tracheal intubation in a patient with Guillain-Barre syndrome","volume":"1991","author":"Pearse","year":"2003","journal-title":"Br J Anaesth"},{"key":"S0317167100004790_manual_ref-6","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(200004)23:4<613::AID-MUS21>3.0.CO;2-4"},{"key":"S0317167100004790_manual_ref-8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/bmb\/ldh042","article-title":"Non-invasive ventilation for acute respiratory disease","volume":"72","author":"Elliott","year":"2004","journal-title":"Br Med Bull"},{"key":"S0317167100004790_manual_ref-4","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2003.297"},{"key":"S0317167100004790_manual_ref-3","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000033797.79530.16"},{"key":"S0317167100004790_manual_ref-7","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1001\/archneur.60.7.947","article-title":"Emergency intubationfor respiratory failure in Guillain-Barre syndrome","volume":"60","author":"Wijdicks","year":"2003","journal-title":"Arch Neurol"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167100004790","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T23:38:24Z","timestamp":1750462704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167100004790\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0317167100004790"],"URL":"https:\/\/doi.org\/10.1017\/s0317167100004790","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}