{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T23:07:40Z","timestamp":1769123260487,"version":"3.49.0"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"unspecified","delay-in-days":3226,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title>\n\t  <jats:sec id=\"S0317167100004819_abs1\">\n\t    <jats:title>Background:<\/jats:title>\n\t    <jats:p>A 61-year-old woman with Parkinson's disease, receiving pergolide 1.75 mg four times daily, was admitted with progressive dyspnea.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0317167100004819_abs2\">\n\t    <jats:title>Methods:<\/jats:title>\n\t    <jats:p>Investigations revealed mitral and aortic regurgitation. She underwent surgical mitral replacement and aortic repair, but had a postoperative course characterized by repeated bouts of congestive heart failure.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0317167100004819_abs3\">\n\t    <jats:title>Results:<\/jats:title>\n\t    <jats:p>Severe tricuspid valve (TV) regurgitation developed within one month after the TV was reported on echocardiography to be relatively normal. Subsequent discontinuation of pergolide was associated with symptomatic improvement.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0317167100004819_abs4\">\n\t    <jats:title>Conclusions:<\/jats:title>\n\t    <jats:p>This case illustrates the severity and rapidity with which cardiac valvular abnormalities can develop in patients receiving pergolide.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/s0317167100004819","type":"journal-article","created":{"date-parts":[[2014,12,12]],"date-time":"2014-12-12T15:30:25Z","timestamp":1418398225000},"page":"111-113","source":"Crossref","is-referenced-by-count":7,"title":["Valvular Heart Disease in Pergolide-Treated Parkinson's Disease"],"prefix":"10.1017","volume":"33","author":[{"given":"James","family":"Scozzafava","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lakshmi","family":"Puttagunta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.R. 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