{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T23:11:52Z","timestamp":1780355512362,"version":"3.54.1"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"unspecified","delay-in-days":6803,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[1997,2]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title><jats:sec id=\"S0317167100021156_abs1\"><jats:title>Background:<\/jats:title><jats:p>Tuberculosis of the nervous system has protean manifestations. Syringomyelia, though an uncommon complication of it, is usually of late onset.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100021156_abs2\"><jats:title>Methods:<\/jats:title><jats:p>We report two patients with tuberculosis meningitis who developed syringomyelia acutely. The diagnosis was supported by neuroimaging and findings at laminectomy.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100021156_abs3\"><jats:title>Results:<\/jats:title><jats:p>The two patients developed syringomyelia between 11 days and 6 weeks of the onset of tuberculous meningitis. They both had cord swelling and softening<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100021156_abs4\"><jats:title>Conclusions:<\/jats:title><jats:p>Acute-onset syringomyelia should be suspected in any patient being treated for tuberculosis meningitis who subsequently develops limb weakness and\/or sphincteric dysfunction. Inflammatory edema and cord ischemia appeared to be the underlying mechanisms in these early onset cases rather than arachnoiditis which is important in late-onset cases.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0317167100021156","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T04:09:18Z","timestamp":1455682158000},"page":"73-76","source":"Crossref","is-referenced-by-count":16,"title":["Syringomyelia Developing as an Acute Complication of Tuberculous Meningitis"],"prefix":"10.1017","volume":"24","author":[{"given":"Abdu Kader","family":"Daif","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Al","family":"Rajeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adesola","family":"Ogunniy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer Al","family":"Boukai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman Al","family":"Tahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S0317167100021156_ref012","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.6.551"},{"key":"S0317167100021156_ref008","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1017\/S0317167100042608","article-title":"Syringomyelia as a complication of tuberculous meningitis","volume":"19","author":"Fehlings","year":"1992","journal-title":"Can J Neurol Sci"},{"key":"S0317167100021156_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(91)90100-L"},{"key":"S0317167100021156_ref015","first-page":"484","volume-title":"Principles of Neurology","author":"Adams","year":"1993"},{"key":"S0317167100021156_ref010","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.44.11.964"},{"key":"S0317167100021156_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/0303-8467(92)90109-G"},{"key":"S0317167100021156_ref006","first-page":"443","article-title":"Tuberculous meningitis","volume":"8","author":"Kocen","year":"1977","journal-title":"Br J Hosp Med"},{"key":"S0317167100021156_ref003","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/17.6.987"},{"key":"S0317167100021156_ref014","first-page":"560","article-title":"Acute paraplegia and intramedullary cavitation in a patient with pulmonary tuberculosis","volume":"52","author":"Schapira","year":"1992","journal-title":"Medicina B Aires"},{"key":"S0317167100021156_ref016","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-199406000-00004"},{"key":"S0317167100021156_ref001","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199507273330406"},{"key":"S0317167100021156_ref004","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1979.03290290032021"},{"key":"S0317167100021156_ref011","first-page":"443","article-title":"Syringomyelia and syringobulbia","volume":"6","author":"Nogu\u00e9s","year":"1987","journal-title":"Handbook of Clinical Neurology.Elsevier Science Publishers Amsterdam BV"},{"key":"S0317167100021156_ref007","doi-asserted-by":"publisher","DOI":"10.1007\/BF00314677"},{"key":"S0317167100021156_ref005","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.2.106"},{"key":"S0317167100021156_ref009","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.58.6.649"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167100021156","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T13:39:29Z","timestamp":1567604369000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167100021156\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,2]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,2]]}},"alternative-id":["S0317167100021156"],"URL":"https:\/\/doi.org\/10.1017\/s0317167100021156","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,2]]}}}