{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T03:16:05Z","timestamp":1794021365622,"version":"4.8.0"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"unspecified","delay-in-days":6622,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[1997,8]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title><jats:sec id=\"S031716710002182X_abs1\"><jats:title>Objective:<\/jats:title><jats:p>To determine the epidemiological profile for pediatric pseudotumor cerebri.<\/jats:p><\/jats:sec><jats:sec id=\"S031716710002182X_abs2\"><jats:title>Methods:<\/jats:title><jats:p>A retrospective case series was identified from a geographically limited region of 205,765 children aged 2-15 years at the only tertiary care pediatric hospital with all pediatric neurologists and ophthalmologists. Health records identified 35 children with ICD9 code 348.2 (benign intracranial hypertension) presenting between April 1, 1979 and March 31, 1994. After chart review, 29 cases were identified which satisfied modified Dandy's diagnostic criteria for pseudotumor cerebri.<\/jats:p><\/jats:sec><jats:sec id=\"S031716710002182X_abs3\"><jats:title>Results:<\/jats:title><jats:p>The 29 cases ranged in age from 3-15 years. The annual incidence of symptomatic disease was 0.9 per 100,000 children (95% Cl 0.6, 1.4). Cases were 2.7 times more likely to be female (21\/29, X\u00b2 p = .01) and twice as likely to be adolescent (age 12-15 years), (X\u00b2 p = .04). Based upon these distinctions, the following estimates of age and sex specific disease incidence were derived (based upon 100,000 child years of exposure): male age 2-11 years: 0.4; male age 12-15 years: 0.8; female age 2-11 years: 1.1; female age 12-16 years: 2.2.<\/jats:p><\/jats:sec><jats:sec id=\"S031716710002182X_abs4\"><jats:title>Conclusions:<\/jats:title><jats:p>These data appear to be unique for its the estimation of age and sex specific incidence rates for pediatric pseudotumor cerebri.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s031716710002182x","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T09:26:22Z","timestamp":1455701182000},"page":"219-221","source":"Crossref","is-referenced-by-count":115,"title":["Pediatric Pseudotumor Cerebri: Descriptive Epidemiology"],"prefix":"10.1017","volume":"24","member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S031716710002182X_ref013","first-page":"1243","article-title":"Pseudotumor cerebri of childhood","volume":"131","author":"Weisberg","year":"1977","journal-title":"Am J Dis Child"},{"key":"S031716710002182X_ref021","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.2_Part_1.239"},{"key":"S031716710002182X_ref020","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1990.00530030091021"},{"key":"S031716710002182X_ref008","first-page":"541","article-title":"Pseudotumor cerebri (clinical profile and visual outcome in 63 patients)","volume":"55","author":"Rush","year":"1980","journal-title":"Mayo Clin Proc"},{"key":"S031716710002182X_ref005","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/ajcn\/46.5.736","article-title":"Development of normalized curves for the international growth reference: historical and technical considerations","volume":"46","author":"Dibley","year":"1987","journal-title":"Am J Clin Nutr"},{"key":"S031716710002182X_ref011","doi-asserted-by":"publisher","DOI":"10.1136\/adc.46.249.651"},{"key":"S031716710002182X_ref012","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1542\/peds.39.2.227","article-title":"Benign intracranial hypertension in children","volume":"39","author":"Rose","year":"1967","journal-title":"Pediatrics"},{"key":"S031716710002182X_ref004","article-title":"Epi Info, Version 6: A word processing, database, and statistics program for epidemiology on microcomputers","author":"Dean","year":"1994","journal-title":"Centers for Disease Control and Prevention, Atlanta, Georgia, USA"},{"key":"S031716710002182X_ref014","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1970.tb09012.x"},{"key":"S031716710002182X_ref019","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1994.02170070019003"},{"key":"S031716710002182X_ref007","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1988.00520320065016"},{"key":"S031716710002182X_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(92)90134-F"},{"key":"S031716710002182X_ref015","first-page":"144","volume":"9","author":"Babikian","year":"1994","journal-title":"Idiopathic intracranial hypertension in children: the Iowa experience"},{"key":"S031716710002182X_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80440-X"},{"key":"S031716710002182X_ref003","volume-title":"Statistical methods for rates and proportions","author":"Fleiss","year":"1981"},{"key":"S031716710002182X_ref018","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330400316"},{"key":"S031716710002182X_ref010","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-199402000-00013"},{"key":"S031716710002182X_ref009","unstructured":"Wall M , George D . Idiopathic intracranial hypertension. Brain 1991; 114: 155\u2013180."},{"key":"S031716710002182X_ref022","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100046588"},{"key":"S031716710002182X_ref001","first-page":"55","article-title":"Whence pseudotumor cerebri?","volume":"5","author":"Smith","year":"1985","journal-title":"J Clin Neuro-Opthalmol"},{"key":"S031716710002182X_ref006","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1993.00540010072020"},{"key":"S031716710002182X_ref002","volume-title":"The Nation: Age, Sex and Marital Status","year":"1987"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S031716710002182X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T10:09:06Z","timestamp":1654337346000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S031716710002182X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,8]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,8]]}},"alternative-id":["S031716710002182X"],"URL":"https:\/\/doi.org\/10.1017\/s031716710002182x","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,8]]}}}