{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T01:51:06Z","timestamp":1648864266257},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"unspecified","delay-in-days":13470,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[1978,11]]},"abstract":"<jats:title>SUMMARY:<\/jats:title><jats:p>A case of a primary intracranial embryonal carcinoma, the first with ultrastructural study, is reported. The tumor was associated with precocious puberty in a 6\u00bd-year-old female. Characteristic embryoid bodies were present. At the ultrastructural level three cell types were noted: undifferentiated, differentiated, and intermediate types. The undifferentiated showed scanty cytoplasmic organelles and numerous free polysomes, while the differentiated cells contained well-developed mitochondria, Golgi apparatus, rough endoplasmic reticulum, and some contained secretory granules. The intermediate cells possessed dilated and irregularly-shaped mitochondria but still retained large numbers of free polysomes. The authors suggest that intracranial germ cell tumors be named in conformity with germ cell tumors in other sites, and that terms such as \u201cectopic pinealoma\u201d and \u201catypical teratoma of the pineal\u201d be used no longer.<\/jats:p>","DOI":"10.1017\/s0317167100024252","type":"journal-article","created":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T11:32:57Z","timestamp":1469705577000},"page":"447-450","source":"Crossref","is-referenced-by-count":4,"title":["Case Report and Ultrastructural Study of Intracranial Embryonal Carcinoma"],"prefix":"10.1017","volume":"5","author":[{"given":"Gerson","family":"Ejeckam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret G.","family":"Norman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie P.","family":"Ivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S0317167100024252_ref020","doi-asserted-by":"publisher","DOI":"10.1111\/apm.1965.64.4.407"},{"key":"S0317167100024252_ref019","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197411)34:5<1722::AID-CNCR2820340521>3.0.CO;2-F"},{"key":"S0317167100024252_ref017","first-page":"1553","article-title":"The ultrastructure of primordial germinal cells of the fetal testes and embryonal carcinoma of cells in mice","volume":"24","author":"Pierce","year":"1964","journal-title":"Cancer Res"},{"key":"S0317167100024252_ref016","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196612)19:12<1963::AID-CNCR2820191224>3.0.CO;2-G"},{"key":"S0317167100024252_ref018","first-page":"285","volume-title":"Pathology of tumors of the nervous system","author":"Russell","year":"1977"},{"key":"S0317167100024252_ref015","first-page":"417","article-title":"On the relation of a typical pinealomas to teratoid tumors","volume":"40","author":"L\u00f8ken","year":"1957","journal-title":"Acta path microbiol scand"},{"key":"S0317167100024252_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(77)80115-9"},{"key":"S0317167100024252_ref012","first-page":"1544","article-title":"Multipotentiality of single embryonal carcinoma cells","volume":"24","author":"Kleinsmith","year":"1964","journal-title":"Cancer Res"},{"key":"S0317167100024252_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(75)90088-5"},{"key":"S0317167100024252_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)66116-4"},{"key":"S0317167100024252_ref007","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195305)6:3<427::AID-CNCR2820060302>3.0.CO;2-U"},{"key":"S0317167100024252_ref006","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700920102"},{"key":"S0317167100024252_ref004","doi-asserted-by":"publisher","DOI":"10.1002\/path.1710970126"},{"key":"S0317167100024252_ref003","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/57.4.511"},{"key":"S0317167100024252_ref002","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197105)27:5<1231::AID-CNCR2820270531>3.0.CO;2-L"},{"key":"S0317167100024252_ref001","first-page":"32","article-title":"Primary intracranial germ cell tumors including five cases of endodermal sinus tumor","volume":"233","author":"Albrechtsen","year":"1972","journal-title":"Acta Path Microbiol Scand"},{"key":"S0317167100024252_ref021","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197102)27:2<391::AID-CNCR2820270223>3.0.CO;2-H"},{"key":"S0317167100024252_ref009","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195103)4:2<265::AID-CNCR2820040211>3.0.CO;2-X"},{"key":"S0317167100024252_ref005","first-page":"1","article-title":"The pathology of testicular tumors","author":"Collins","year":"1964","journal-title":"BrJ Urol"},{"key":"S0317167100024252_ref011","doi-asserted-by":"publisher","DOI":"10.1007\/BF00685269"},{"key":"S0317167100024252_ref013","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197612)38:6<2420::AID-CNCR2820380630>3.0.CO;2-2"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167100024252","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T19:20:25Z","timestamp":1558984825000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167100024252\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,11]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,11]]}},"alternative-id":["S0317167100024252"],"URL":"https:\/\/doi.org\/10.1017\/s0317167100024252","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,11]]}}}