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The MS patients were classified as definite (n = 31), probable (n = 31) and possible (n = 27).<\/jats:p><jats:p>The aim of this study was to determine the diagnostic value of the five electrophysiological tests in MS. VER and ABER recordings were found to reveal the highest number of asymptomatic abnormalities (33 and 31 percent respectively). The combination of VER, ABER and ENG revealed all possible electrophysiological disorders. As these tests are completely non-invasive it is proposed, that a combination of two of these three tests is useful for the detection of a second silent lesion in patients with suspected MS showing purely spinal signs (VER, ENG, ABER) and\/or a history of uncomplicated ON (ABER, ENG).<\/jats:p>","DOI":"10.1017\/s0317167100035393","type":"journal-article","created":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T07:37:16Z","timestamp":1469691436000},"page":"308-313","source":"Crossref","is-referenced-by-count":9,"title":["Electrophysiological Disorders in Multiple Sclerosis and Optic Neuritis"],"prefix":"10.1017","volume":"12","author":[{"given":"E.A.C.M.","family":"Sanders","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.H.","family":"Reulen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.A.H.","family":"Hogenhuis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.A.","family":"van der Velde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S0317167100035393_ref039","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(78)90004-7"},{"key":"S0317167100035393_ref031","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(80)90152-2"},{"key":"S0317167100035393_ref012","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1982.00510230022007"},{"key":"S0317167100035393_ref001","article-title":"Multiple nicht eitrige Encephalomyelitis und Multiple Sclerose","volume":"12","author":"Anton","year":"1912","journal-title":"Zeitschrift f\u00fcr d ges Neurol u Psychiat"},{"key":"S0317167100035393_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(78)90048-5"},{"key":"S0317167100035393_ref025","doi-asserted-by":"publisher","DOI":"10.1038\/252230a0"},{"key":"S0317167100035393_ref018","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/94.4.681"},{"key":"S0317167100035393_ref027","volume-title":"Multiple Sclerosis. 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