{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T09:30:38Z","timestamp":1778232638881,"version":"3.51.4"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"unspecified","delay-in-days":7261,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[1995,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0317167100039561_abs1\"><jats:title><jats:italic><jats:bold>Background<\/jats:bold><\/jats:italic><\/jats:title><jats:p>Ependymomas usually arise from the ventricular surface.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100039561_abs2\"><jats:title><jats:italic><jats:bold>Methods<\/jats:bold><\/jats:italic><\/jats:title><jats:p>We report an 11-year-old female who presented with a supratentorial ectopic ependymoma.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100039561_abs3\"><jats:title><jats:italic><jats:bold>Results<\/jats:bold><\/jats:italic><\/jats:title><jats:p>The patient presented with a two-month-history of progressive headache, nausea and vomiting. Examination revealed papilledema, horizontal nystagmus, diplopia on upward gaze, and right pronator drift. CT scan showed an enhancing left precentral subcortical lesion measuring 3 cm in diameter with associated edema and mass effect. Its medial border was located 3 cm from the ependymal surface of the ventricle. A firm tumour was dissected from the centrum semiovale white matter, and removed <jats:italic>in toto<\/jats:italic> as confirmed on MRI. Pathological examination revealed histological, immuno-histochemical and electron microscopic features consistent with an ependymoma. Spine MRI and bone marrow aspirate, as well as lumbar puncture of cytology failed to show any dissemination.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100039561_abs4\"><jats:title><jats:italic><jats:bold>Conclusion<\/jats:bold><\/jats:italic><\/jats:title><jats:p>From the literature review, this represents an exceptional ependymoma located at the distance from the ventricular system or cisterns. Different pathogenic alternatives are discussed.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0317167100039561","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T04:24:09Z","timestamp":1455683049000},"page":"316-319","source":"Crossref","is-referenced-by-count":28,"title":["Supratentorial Ectopic Ependymoma"],"prefix":"10.1017","volume":"22","author":[{"given":"Olivier","family":"Vernet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Pierre","family":"Farmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Meagher-Villemure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 L.","family":"Montes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S0317167100039561_ref374","volume-title":"Atlas of tumour pathology: tumours of the central nervous system","volume":"1994","author":"Burger"},{"key":"S0317167100039561_ref378","first-page":"31","article-title":"Extension of posterior fossa tumours, particularly intraventricular fourth ventricle tumours, into the upper cervical spinal canal","volume":"110","author":"Epstein","year":"1970","journal-title":"Am J Radiol"},{"key":"S0317167100039561_ref377","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1961.18.6.0792"},{"key":"S0317167100039561_ref386","doi-asserted-by":"publisher","DOI":"10.1007\/BF00687216"},{"key":"S0317167100039561_ref362","first-page":"428","article-title":"Ependymomas","volume":"33","author":"Barone","year":"1970","journal-title":"A clinical survey"},{"key":"S0317167100039561_ref384","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.40.2.127"},{"key":"S0317167100039561_ref387","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1968.28.2.0129"},{"key":"S0317167100039561_ref385","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1974.41.1.0075"},{"key":"S0317167100039561_ref367","first-page":"154","article-title":"Intracranial ependymomas in children. 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