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There were 25 infratentorial tumours and 182 supratentorial tumours (39 deep and 143 superficial). The total number of patients sustaining complications was 52 for an overall complication rate of 25.1%; the rate was higher for infratentorial tumours (44.0%) than supratentorial tumours (22.8%) regardless of histology (p = 0.012). There were 5 deaths for a mortality rate of 2.4%. Forty-seven patients incurred operative morbidity (22.7%); 7 out of the 47 had multiple complications. Sixteen patients sustained transient worsening due to edema (7.7%) and 6 patients sustained permanent neurological deficit (2.9%). Medical complications were suffered by 17 patients (8.2%). Major complications which significantly altered the quality and\/or quantity of survival were suffered by 9 patients overall (4.3%).<\/jats:p>","DOI":"10.1017\/s0317167100041184","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T09:19:53Z","timestamp":1455700793000},"page":"213-218","source":"Crossref","is-referenced-by-count":109,"title":["Complications of First Craniotomy for Intra-Axial Brain Tumour"],"prefix":"10.1017","volume":"21","author":[{"given":"Alberto M.","family":"Cabantog","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S0317167100041184_ref196","first-page":"1052","article-title":"A review of brain retraction and recommendations for minimizing intraoperative brain injury","volume":"33","author":"Andrews","year":"1993","journal-title":"Neurosurgery"},{"key":"S0317167100041184_ref194","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.9.1374"},{"key":"S0317167100041184_ref189","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199304000-00010"},{"key":"S0317167100041184_ref185","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.78.5.0762"},{"key":"S0317167100041184_ref184","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198801000-00002"},{"key":"S0317167100041184_ref183","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198908000-00006"},{"key":"S0317167100041184_ref176","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198708000-00012"},{"key":"S0317167100041184_ref174","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1987.66.6.0865"},{"key":"S0317167100041184_ref170","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1964.21.6.0497"},{"key":"S0317167100041184_ref169","author":"Cushing","year":"1932"},{"key":"S0317167100041184_ref191","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1983.58.5.0666"},{"key":"S0317167100041184_ref193","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19800515)45:10<2639::AID-CNCR2820451025>3.0.CO;2-O"},{"key":"S0317167100041184_ref182","doi-asserted-by":"publisher","DOI":"10.1007\/BF01402111"},{"key":"S0317167100041184_ref179","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.78.5.0767"},{"key":"S0317167100041184_ref197","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1983.58.5.0672"},{"key":"S0317167100041184_ref188","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199002223220802"},{"key":"S0317167100041184_ref175","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.73.3.0331"},{"key":"S0317167100041184_ref198","first-page":"55","article-title":"Post-operative epilepsy and the efficacy of anticonvulsant therapy","volume":"50","author":"Shaw","year":"1990","journal-title":"Acta Neurochir, Suppl"},{"key":"S0317167100041184_ref186","first-page":"636","article-title":"Treatment and survival of low-grade astrocytoma in adults \u2013 1977\u20131988","volume":"31","author":"McCormack","year":"1992","journal-title":"Neurosurgery"},{"key":"S0317167100041184_ref172","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1960.17.4.0736"},{"key":"S0317167100041184_ref180","first-page":"597","volume-title":"Neurosurgery","author":"Galicich","year":"1985"},{"key":"S0317167100041184_ref187","first-page":"129","article-title":"Surgery of cerebral gliomas. 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