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In considering the possible role of heredity in Parkinson\u2019s disease it is necessary to carefully distinguish between the disease and other disorders such as essential tremor and olivopontocerebellar atrophy which may manifest parkinsonian features. Controlled family studies have shown only a very slight excess of secondary cases among index siblings as compared to spouse siblings. The concordance rate for Parkinson\u2019s disease among identical twins is extraordinarily low and does not significantly exceed that among fraternal twins or that expected from the prevalence rate among siblings found in the controlled family studies. The available evidence indicates that heredity plays no significant role in the etiology of Parkinson\u2019s disease. Consequently the disease must be considered to be acquired.<\/jats:p>","DOI":"10.1017\/s031716710004631x","type":"journal-article","created":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T11:36:04Z","timestamp":1469705764000},"page":"151-155","source":"Crossref","is-referenced-by-count":37,"title":["Is Parkinson\u2019s Disease Acquired or Inherited?"],"prefix":"10.1017","volume":"11","author":[{"given":"Roger C.","family":"Duvoisin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S031716710004631X_ref529","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.33.7.815"},{"key":"S031716710004631X_ref513","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1982.00510240012003"},{"key":"S031716710004631X_ref527","first-page":"184","article-title":"Sur la notion d\u2019heredite similaire dans la maladie de Parkinson","volume":"80","author":"Scarpalezos","year":"1948","journal-title":"Rev. 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