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The pathophysiology of this multisystem disorder is unknown, although the M-protein is essential. No improvement was found after radiation, chemotherapy and steroid treatment.<\/jats:p>","DOI":"10.1017\/s0317167100048794","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T09:12:27Z","timestamp":1455700347000},"page":"60-63","source":"Crossref","is-referenced-by-count":7,"title":["Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy and Skin Changes (Poems) Syndrome"],"prefix":"10.1017","volume":"21","author":[{"given":"I.","family":"Milanov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Georgiev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S0317167100048794_ref014","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199212313272705"},{"key":"S0317167100048794_ref021","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670050039016"},{"key":"S0317167100048794_ref001","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198007000-00006"},{"key":"S0317167100048794_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)70678-6"},{"key":"S0317167100048794_ref002","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.6.712"},{"key":"S0317167100048794_ref016","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199003083221002"},{"key":"S0317167100048794_ref008","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.33.2.202"},{"key":"S0317167100048794_ref005","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.140.1.7244223"},{"key":"S0317167100048794_ref009","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1978.tb14877.x"},{"key":"S0317167100048794_ref007","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.1.24"},{"key":"S0317167100048794_ref020","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1987.tb04933.x"},{"key":"S0317167100048794_ref004","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.4.532"},{"key":"S0317167100048794_ref006","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.7.675"},{"key":"S0317167100048794_ref019","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1001\/archderm.1987.01660250091026","article-title":"The skin changes in the Crow-Fukase (POEMS) syndrome","volume":"123","author":"Shelly","year":"1987","journal-title":"Arch Dermatol"},{"key":"S0317167100048794_ref018","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1056\/NEJM198510173131616","article-title":"Accelerated conversion of androgen to estrogen in plasma cell dyscrasia associated with polyneuropathy, anasarca, and skin pigmentation.","volume":"313","author":"Matsumine","year":"1985","journal-title":"Engl J Med"},{"key":"S0317167100048794_ref010","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198007000-00005"},{"key":"S0317167100048794_ref011","doi-asserted-by":"publisher","DOI":"10.1080\/22953337.1987.11719222"},{"key":"S0317167100048794_ref012","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1980.tb01167.x"},{"key":"S0317167100048794_ref013","doi-asserted-by":"publisher","DOI":"10.1007\/BF00839213"},{"key":"S0317167100048794_ref015","doi-asserted-by":"publisher","DOI":"10.1007\/BF00227726"},{"key":"S0317167100048794_ref017","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.4.614"},{"key":"S0317167100048794_ref022","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-84-3-271"},{"key":"S0317167100048794_ref023","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111213252105"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167100048794","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T19:24:33Z","timestamp":1557948273000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167100048794\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,2]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1994,2]]}},"alternative-id":["S0317167100048794"],"URL":"https:\/\/doi.org\/10.1017\/s0317167100048794","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,2]]}}}