{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T08:24:33Z","timestamp":1695630273428},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"unspecified","delay-in-days":5873,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[2001,2]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title><jats:sec id=\"S0317167100052586_abs1\"><jats:title>Objective:<\/jats:title><jats:p>Behcet's disease is the association of recurrent aphthous stomatitis with genital ulceration and eye disease. Neurologic involvement patterns include meningomyelitis, a brain stem syndrome, pyramidal and extrapyramidal abnormality and stroke. In the present study, subclinical involvement was investigated by using P300 in Behcet's patients without neurological manifestation.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100052586_abs2\"><jats:title>Methods:<\/jats:title><jats:p>Fifteen patients and 15 healthy volunteers were accepted for the study. P300 from vertex (Cz) electrode sites of the 10-20 system using electrodes and motor response time were recorded.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100052586_abs3\"><jats:title>Results:<\/jats:title><jats:p>Patients had significantly prolonged latencies of P300 as compared to normal controls (p=0.013) but no significant differences in amplitude (p=1.000). Patients showed a significantly delayed motor response time than controls (p=0.006). Nine patients (60 %) had P300 latency and eight patients (53.3 %) had motor response time values exceeding the mean of controls by two standard deviations.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100052586_abs4\"><jats:title>Conclusion:<\/jats:title><jats:p>The findings suggest that the P300 measures and motor response time may reflect subclinical neurologic involvement in Behcet's disease.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0317167100052586","type":"journal-article","created":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T07:05:31Z","timestamp":1488524731000},"page":"66-69","source":"Crossref","is-referenced-by-count":12,"title":["P300 in Behcet's Patients without Neurological 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