{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:18:41Z","timestamp":1757542721019},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T00:00:00Z","timestamp":1455580800000},"content-version":"unspecified","delay-in-days":4308,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0317167100053981_abs1\"><jats:title>Objective:<\/jats:title><jats:p>To report a case of spinal intramedullary blastomycosis causing myelopathy. This is the first published case of a pediatric patient with intramedullary blastomycosis and compromised function.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100053981_abs2\"><jats:title>Clinical presentation:<\/jats:title><jats:p>An otherwise healthy 13-year-old patient was diagnosed with respiratory North American blastomycosis. She subsequently received a five-month course of itraconazole with presumed resolution of the infection. The patient presented again at 14 years of age with a lumbar myelopathy. Magnetic resonance imaging revealed an intramedullary lesion of 1 cm diameter at the level of T12-L1.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100053981_abs3\"><jats:title>Intervention:<\/jats:title><jats:p>AT12-L1 laminectomy was performed with a gross total resection of the lesion. Pathological examination and microbiological culture of the specimen was consistent with blastomycosis. Postoperatively, the patient was placed on a five week course of amphotericin B. The patient showed substantial improvement in neurological function.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167100053981_abs4\"><jats:title>Conclusion:<\/jats:title><jats:p>Blastomycosis can present as an isolated intramedullary lesion causing compromised function. It should be considered in the differential diagnosis of a patient with a myelopathy and previously recognized blastomycosis. The prognosis is good with surgical resection.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0317167100053981","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T04:27:41Z","timestamp":1455683261000},"page":"282-285","source":"Crossref","is-referenced-by-count":10,"title":["Intramedullary Blastomycosis in a Child: Case Report"],"prefix":"10.1017","volume":"31","author":[{"given":"A.M.","family":"Parr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Fewer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,2,16]]},"reference":[{"key":"S0317167100053981_ref014","first-page":"2733","volume-title":"Principles and Practice of Infectious Diseases","author":"Chapman","year":"2000"},{"key":"S0317167100053981_ref010","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/23.9.890"},{"key":"S0317167100053981_ref008","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199509000-00027"},{"key":"S0317167100053981_ref007","first-page":"1898","article-title":"Blastomycosis","author":"Thomas","year":"1992","journal-title":"Textbook of Pediatric Infectious Diseases"},{"key":"S0317167100053981_ref004","doi-asserted-by":"publisher","DOI":"10.1086\/clinids\/26.2.413"},{"key":"S0317167100053981_ref002","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.Supplement_1.S82"},{"key":"S0317167100053981_ref012","first-page":"275","article-title":"Blastomycosis. 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A review of the literature","volume":"39","author":"Martin","year":"1939","journal-title":"Am Rev Tuberc"},{"key":"S0317167100053981_ref013","volume-title":"Goodman and Gilman\u2019s The Pharmacological Basis of Therapeutics","author":"Hardman","year":"2001"},{"key":"S0317167100053981_ref005","doi-asserted-by":"publisher","DOI":"10.1007\/s005860050100"},{"key":"S0317167100053981_ref003","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196805000-00001"},{"key":"S0317167100053981_ref011","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410030106"},{"key":"S0317167100053981_ref009","doi-asserted-by":"publisher","DOI":"10.3109\/00365549409008601"},{"key":"S0317167100053981_ref001","doi-asserted-by":"publisher","DOI":"10.1086\/340049"},{"key":"S0317167100053981_ref006","first-page":"489","article-title":"Infections of the spine","author":"Colombo","year":"1992","journal-title":"Imaging of the Spine and Spinal Cord"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167100053981","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T17:14:10Z","timestamp":1557162850000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167100053981\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["S0317167100053981"],"URL":"https:\/\/doi.org\/10.1017\/s0317167100053981","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}