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In addition to a systematic analysis of the walking gait of animals, tests for activity, catalepsy, rigidity, and various reflexive responses were included in the battery. The standardization and validation of the test system was performed by determining and comparing profiles of neurobehavioral effects produced by 3-acetyl pyridine, acrylamide, pyrithiamine, and thiamine deficiency, four experimental treatments reported to induce ataxia in animals. Results indicate that profiles of neurobehavioral disturbances accompanying ataxia in animals varied distinctively with each experimental treatment.<\/jats:p>","DOI":"10.1017\/s0317167100119663","type":"journal-article","created":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T11:33:04Z","timestamp":1469705584000},"page":"209-215","source":"Crossref","is-referenced-by-count":53,"title":["Measurement of Ataxia and Related Neurological Signs in the Laboratory Rat"],"prefix":"10.1017","volume":"6","author":[{"given":"F.B.","family":"Jolicoeur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.B.","family":"Rondeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Hamel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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