{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:41:00Z","timestamp":1792806060387,"version":"4.5.0"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"S1","license":[{"start":{"date-parts":[[2016,4,19]],"date-time":"2016-04-19T00:00:00Z","timestamp":1461024000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Can. J. Aging"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>R\u00c9SUM\u00c9<\/jats:title><jats:p>Avec le nombre croissant de conducteurs \u00e2g\u00e9s pour lesquelles on prescrit des antid\u00e9presseurs, les cons\u00e9quences potentielles de l\u2019utilisation des antid\u00e9presseurs sur les comp\u00e9tences de conduite dans une population vieillissante deviennent un probl\u00e8me urgent. Nous avons effectu\u00e9 une analyse syst\u00e9matique en utilisant MEDLINE, ciblant des articles qui se rapportent sp\u00e9cifiquement aux antid\u00e9presseurs et \u00e0 la conduite dans une population ou sous-groupe de personnes \u00e2g\u00e9es (\u2265 55 ans d\u2019\u00e2ge). La recherche a retourn\u00e9 267 r\u00e9f\u00e9rences, dont neuf portaient sur les effets des antid\u00e9presseurs sur la conduite chez les personnes \u00e2g\u00e9es. L\u2019\u00e9tude exp\u00e9rimentale unique a trouv\u00e9 que imipramine exerce des effets n\u00e9fastes sur la conduite sur autoroute, alors que la n\u00e9fazodone n\u2019a pas fait. Sept des huit \u00e9tudes de population ont rapport\u00e9 une augmentation significative du risque d\u2019\u00eatre impliqu\u00e9 dans une collision associ\u00e9 \u00e0 l\u2019utilisation des antid\u00e9presseurs. Bien que les \u00e9tudes ont indiqu\u00e9 un effet n\u00e9gatif des antid\u00e9presseurs sur la conduite, les conceptions \u00e9pid\u00e9miologiques ne peuvent pas exclure la possibilit\u00e9 que la maladie sous-jacente, qui est g\u00e9n\u00e9ralement la d\u00e9pression majeure, est la coupable.<\/jats:p>","DOI":"10.1017\/s0714980816000064","type":"journal-article","created":{"date-parts":[[2016,4,19]],"date-time":"2016-04-19T07:23:26Z","timestamp":1461050606000},"page":"7-14","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Antidepressants and Driving in Older Adults: A Systematic Review"],"prefix":"10.1017","volume":"35","author":[{"given":"Duncan H.","family":"Cameron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Rapoport","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,4,19]]},"reference":[{"key":"S0714980816000064_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00004850-199409000-00008"},{"key":"S0714980816000064_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2014.11.004"},{"key":"S0714980816000064_ref7","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/j.1532-5415.2012.03923.x","article-title":"American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults","volume":"60","author":"Fick","year":"2012","journal-title":"Journal of the American Geriatrics Society"},{"key":"S0714980816000064_ref3","volume-title":"National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Data","year":"2012"},{"key":"S0714980816000064_ref20","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v64n0106"},{"key":"S0714980816000064_ref28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001463"},{"key":"S0714980816000064_ref23","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e31820d93f9"},{"key":"S0714980816000064_ref26","doi-asserted-by":"publisher","DOI":"10.1177\/001872089203400105"},{"key":"S0714980816000064_ref25","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/136.7.873"},{"key":"S0714980816000064_ref6","unstructured":"Schulze H. , Schumacher M. , Urmeew R. , & Auerbach K . (2012). Final Report: Work performed, main results and recommendations. DRUID (Driving under the Influence of Drugs, Alcohol and Medicines) Deliverable 0.1, 8. Retrieved from http:\/\/www.druid-project.eu\/ (Accessed January 2015)."},{"key":"S0714980816000064_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2013.08.002"},{"key":"S0714980816000064_ref27","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0749-0690(18)30413-0","article-title":"Medications and the older driver","volume":"9","author":"Ray","year":"1993","journal-title":"Clinics in Geriatric Medicine"},{"key":"S0714980816000064_ref21","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200721060-00006"},{"key":"S0714980816000064_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.12.1475"},{"key":"S0714980816000064_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-4575(98)00019-0"},{"key":"S0714980816000064_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03561.x"},{"key":"S0714980816000064_ref19","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12090"},{"key":"S0714980816000064_ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199411000-00006"},{"key":"S0714980816000064_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.aap.2004.11.003"},{"key":"S0714980816000064_ref29","first-page":"13","article-title":"Driving on antidepressants: Cruising for a crash?","volume":"6","author":"Sansone","year":"2009","journal-title":"Psychiatry"},{"key":"S0714980816000064_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-012-0833-8"},{"key":"S0714980816000064_ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4551"},{"key":"S0714980816000064_ref22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01903.x"},{"key":"S0714980816000064_ref15","first-page":"485","volume-title":"A critical view of driver behavior models: What do we know, what should we do?","author":"Michon","year":"1985"},{"key":"S0714980816000064_ref5","volume-title":"Maintaining safe mobility in an aging society","author":"Eby","year":"2009"},{"key":"S0714980816000064_ref31","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-199502000-00006"},{"key":"S0714980816000064_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2006.01.015"},{"key":"S0714980816000064_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2012.04.002"},{"key":"S0714980816000064_ref17","unstructured":"National Highway Traffic Safety Administration. (2014). Traffic safety facts: A compilation of motor vehicle crash data from the Fatality Analysis Reporting System and the General Estimates System. Retrieved from http:\/\/www-nrd.nhtsa.dot.gov\/Cats\/listpublications.aspx?Id=E&ShowBy=DocType (Accessed January 2015)."},{"key":"S0714980816000064_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsr.2003.09.002"},{"key":"S0714980816000064_ref33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1539-6924.1982.tb01384.x"},{"key":"S0714980816000064_ref18","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.11m07624"},{"key":"S0714980816000064_ref32","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7643-9923-8"}],"container-title":["Canadian Journal on Aging \/ La Revue canadienne du vieillissement"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0714980816000064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T04:17:28Z","timestamp":1555647448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0714980816000064\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,19]]},"references-count":33,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S0714980816000064"],"URL":"https:\/\/doi.org\/10.1017\/s0714980816000064","relation":{},"ISSN":["0714-9808","1710-1107"],"issn-type":[{"value":"0714-9808","type":"print"},{"value":"1710-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,19]]},"assertion":[{"value":"Copyright \u00a9 Canadian Association on Gerontology 2016\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}