{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:31:59Z","timestamp":1792593119882,"version":"4.5.0"},"reference-count":44,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Can. J. Aging"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cumulative exposure to anticholinergic and sedative medications has been associated with worsening physical function in older adults. We evaluated the feasibility of measuring physical function using wearable devices and explored the impact of reducing the anticholinergic and sedative medication burden in a pilot study of community-dwelling adults aged 60 years and older. Evaluations included the 10-meter walk test (10MWT), the Short Physical Performance Battery (SPPB), and the mini-BESTest. Two participants\/month were recruited in one clinic in 2022. The five participants had a median age of 67, a median DBI of 1.7, and four were female. The feasibility analysis showed that the 10MWT and SPPB tests were completed on 12\/12, and the mini-BESTest on 11\/12. An exploratory analysis showed clinically meaningful improvements in gait speed (mean +0.18 m\/s) and SPPB (mean +2.2 points). We showed the feasibility of measuring physical function by wearable devices during deprescribing of anticholinergic and sedative medications.<\/jats:p>","DOI":"10.1017\/s0714980825000078","type":"journal-article","created":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T04:08:52Z","timestamp":1740629332000},"page":"254-261","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility of Measuring Physical Function by Wearable Devices During Deprescribing of Anticholinergic and Sedative Medications"],"prefix":"10.1017","volume":"44","author":[{"given":"Benoit","family":"Cossette","sequence":"first","affiliation":[{"name":"University of Sherbrooke"},{"name":"CIUSSS de l\u2019Estrie-CHUS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Boissy","sequence":"additional","affiliation":[{"name":"University of Sherbrooke"},{"name":"CIUSSS de l\u2019Estrie-CHUS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-H\u00e9l\u00e8ne","family":"Milot","sequence":"additional","affiliation":[{"name":"University of Sherbrooke"},{"name":"CIUSSS de l\u2019Estrie-CHUS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah N","family":"Hilmer","sequence":"additional","affiliation":[{"name":"Kolling Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0927-7295","authenticated-orcid":false,"given":"Lisa","family":"Kouladjian O\u2019Donnell","sequence":"additional","affiliation":[{"name":"Kolling Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danijela","family":"Gnjidic","sequence":"additional","affiliation":[{"name":"The University of Sydney"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Sirois","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Laval"},{"name":"Universit\u00e9 Laval"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dee","family":"Mangin","sequence":"additional","affiliation":[{"name":"McMaster University"},{"name":"University of Otago"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevi\u00e8ve","family":"Ricard","sequence":"additional","affiliation":[{"name":"University of Sherbrooke"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer E.","family":"Isenor","sequence":"additional","affiliation":[{"name":"Dalhousie University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacynthe","family":"Roy-Petit","sequence":"additional","affiliation":[{"name":"CIUSSS de l\u2019Estrie-CHUS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bessam","family":"Abdulrazak","sequence":"additional","affiliation":[{"name":"University of Sherbrooke"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn","family":"Tousignant","sequence":"additional","affiliation":[{"name":"CIUSSS de l\u2019Estrie-CHUS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Lebel","sequence":"additional","affiliation":[{"name":"CIUSSS de l\u2019Estrie-CHUS"},{"name":"University of Sherbrooke"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"S0714980825000078_r36","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-10-1"},{"key":"S0714980825000078_r25","doi-asserted-by":"publisher","DOI":"10.1186\/1743-0003-9-59"},{"key":"S0714980825000078_r15","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.02.021"},{"key":"S0714980825000078_r29","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-023-03820-6"},{"key":"S0714980825000078_r42","first-page":"357","article-title":"Long-term exposure to anticholinergic and sedative medications and cognitive and physical function in later life","volume":"75","author":"Wouters","year":"2020","journal-title":"The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences"},{"key":"S0714980825000078_r30","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2018.1397625"},{"key":"S0714980825000078_r5","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-019-02660-x"},{"key":"S0714980825000078_r8","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0537"},{"key":"S0714980825000078_r11","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20120171"},{"key":"S0714980825000078_r4","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-018-0578-7"},{"key":"S0714980825000078_r12","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/49.2.M85"},{"key":"S0714980825000078_r22","doi-asserted-by":"publisher","DOI":"10.1177\/0091270011421489"},{"key":"S0714980825000078_r21","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2023.03.006"},{"key":"S0714980825000078_r44","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S253177"},{"key":"S0714980825000078_r3","doi-asserted-by":"publisher","DOI":"10.1038\/sj.clpt.6100303"},{"key":"S0714980825000078_r14","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.8.781"},{"key":"S0714980825000078_r9","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2011.573499"},{"key":"S0714980825000078_r24","first-page":"007","article-title":"Mobility Lab to Assess Balance and Gait with Synchronized Body-worn Sensors","volume":"1","author":"Mancini","year":"2011","journal-title":"Journal of Bioengineering and Biomedical Science"},{"key":"S0714980825000078_r32","doi-asserted-by":"publisher","DOI":"10.3109\/11038128.2013.810304"},{"key":"S0714980825000078_r38","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-022-02808-8"},{"key":"S0714980825000078_r27","doi-asserted-by":"publisher","DOI":"10.2196\/15191"},{"key":"S0714980825000078_r13","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/57.4.M217"},{"key":"S0714980825000078_r39","doi-asserted-by":"publisher","DOI":"10.1186\/s13047-022-00521-y"},{"key":"S0714980825000078_r6","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-035656"},{"key":"S0714980825000078_r1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly230"},{"key":"S0714980825000078_r31","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.050051"},{"key":"S0714980825000078_r45","unstructured":"World Health Organization. (2024). Anatomical therapeutic chemical (ATC) classification. Available at: www.whocc.no\/atc_ddd_index\/. Accessed on 17 April 2024."},{"key":"S0714980825000078_r43","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-021-00902-1"},{"key":"S0714980825000078_r18","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/57.4.M209"},{"key":"S0714980825000078_r23","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glaa060"},{"key":"S0714980825000078_r35","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000905"},{"key":"S0714980825000078_r10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2009.03411.x"},{"key":"S0714980825000078_r41","unstructured":"World Health Organization. (2001). International Classification of Functioning, Disability and Health (ICF). www.who.int\/standards\/classifications\/international-classification-of-functioning-disability-and-health. Accessed 2024-04-17."},{"key":"S0714980825000078_r26","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly148"},{"key":"S0714980825000078_r28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2006.00701.x"},{"key":"S0714980825000078_r16","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-019-0166-1"},{"key":"S0714980825000078_r34","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2015.0324"},{"key":"S0714980825000078_r20","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S66660"},{"key":"S0714980825000078_r7","unstructured":"World Health Organization. (2020). Decade of healthy ageing: Baseline report. Geneva: World Health Organization. Licence\u00a0: CC BY-NC-SA 3.0 IGO. www.who.int\/publications\/i\/item\/9789240017900. Accessed on 17 Apr 2024."},{"key":"S0714980825000078_r40","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-018-0549-z"},{"key":"S0714980825000078_r2","doi-asserted-by":"publisher","DOI":"10.1177\/2042098613500689"},{"key":"S0714980825000078_r37","doi-asserted-by":"publisher","DOI":"10.1186\/1743-0003-11-152"},{"key":"S0714980825000078_r19","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2015.11.002"},{"key":"S0714980825000078_r33","doi-asserted-by":"publisher","DOI":"10.1109\/TNSRE.2010.2047606"}],"updated-by":[{"DOI":"10.1017\/s0714980825100093","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000}}],"container-title":["Canadian Journal on Aging \/ La Revue canadienne du vieillissement"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0714980825000078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T08:43:08Z","timestamp":1768898588000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0714980825000078\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,27]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0714980825000078"],"URL":"https:\/\/doi.org\/10.1017\/s0714980825000078","relation":{},"ISSN":["0714-9808","1710-1107"],"issn-type":[{"value":"0714-9808","type":"print"},{"value":"1710-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,27]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press on behalf of The Canadian Association on Gerontology","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is used to distribute the re-used or adapted article and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}