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Infect."],"published-print":{"date-parts":[[1988,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>From January 1983 until December 1985, 35 cases of sporadic nosocomial legionella pneumonia, all caused by<jats:italic>Legionella pneumophila<\/jats:italic>, were diagnosed in a university hospital.<jats:italic>L. pneumophila<\/jats:italic>serogroup (SG) 1 was cultured from 12 of the 35 cases and compared to corresponding<jats:italic>L. pneumophila<\/jats:italic>SG 1 isolates from water outlets in the patients' immediate environment by subtyping with monoclonal antibodies. The corresponding environmental isolates were identical to 9 out of 12 (75%) of those from the cases. However, even in the remaining three cases identical subtypes were found distributed throughout the hospital water supply. From the hospital water supply four different subtypes of<jats:italic>L. pneumophila<\/jats:italic>SG 1 were isolated, three of which were implicated in legionella pneumonia. Of 453 water samples taken during the study 298 (65.8%) were positive for legionellae. Species of<jats:italic>Legionella<\/jats:italic>other than<jats:italic>L. pneumophila<\/jats:italic>have not been isolated. This may explain the exclusiveness of<jats:italic>L<\/jats:italic>.<jats:italic>pneumophila<\/jats:italic>as the legionella pneumonia-causing agent. Our results suggest that the water supply system was the source of infection.<\/jats:p>","DOI":"10.1017\/s0950268800029526","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:32:23Z","timestamp":1242379943000},"page":"647-654","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":26,"title":["Nosocomial legionella pneumonia: demonstration of potable water as the source of infection"],"prefix":"10.1017","volume":"101","author":[{"given":"B.","family":"Ruf","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Sch\u00fcrmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Horbrach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Seodel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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In Legionella Infections","author":"Bartlett","year":"1986"},{"key":"S0950268800029526_ref006","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1128\/jcm.8.3.329-338.1978","article-title":"Detection of Legionnaires' disease bacteria by direct immuno-fluorescent staining","volume":"8","author":"Cherry","year":"1978","journal-title":"Journal of Clinical Microbiology"},{"key":"S0950268800029526_ref009","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1128\/JCM.14.3.298-303.1981","article-title":"Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens","volume":"14","author":"Edelstein","year":"1981","journal-title":"Journal of Clinical Microbiology"},{"key":"S0950268800029526_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0195-6701(86)90037-X"},{"key":"S0950268800029526_ref011","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1128\/JCM.23.6.1121-1126.1986","article-title":"Paleoepidemiologic investigation of Legionnaires disease at Wadsworth veterans administration hospital by using three typing methods for comparision of legionellae from clinical and environmental sources","volume":"23","author":"Edelstein","year":"1986","journal-title":"Journal of Clinical Microbiology"},{"key":"S0950268800029526_ref012","first-page":"706","article-title":"Rapid detection of Legionella antigen in tissues and body fluids","volume":"22","author":"Fehrenbach","year":"1986","journal-title":"Israel Journal of Medical Sciences"},{"key":"S0950268800029526_ref015","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)90349-6"},{"key":"S0950268800029526_ref016","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1128\/JCM.23.4.768-771.1986","article-title":"Development of a standardized subgrouping scheme for Legionella pneumophila serogroup 1 using monoclonal antibodies","volume":"23","author":"Joly","year":"1986","journal-title":"Journal of Clinical Microbiology"},{"key":"S0950268800029526_ref019","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/152.2.356"},{"key":"S0950268800029526_ref020","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03330470024025"},{"key":"S0950268800029526_ref021","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1986.00360200183030"},{"key":"S0950268800029526_ref022","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(85)90399-7"},{"key":"S0950268800029526_ref029","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400063580"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268800029526","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T12:54:14Z","timestamp":1633438454000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268800029526\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,12]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1988,12]]}},"alternative-id":["S0950268800029526"],"URL":"https:\/\/doi.org\/10.1017\/s0950268800029526","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,12]]},"assertion":[{"value":"Cambridge University Press 1988","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}