{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:17:28Z","timestamp":1761488248648},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":6740,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1990,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Piglets between 1 and 40 days of age were inoculated with varying numbers and with different isolates of<jats:italic>Streptococcus suis<\/jats:italic>type 2 by the intranasal, intravenous and subarachnoid routes. Less than 100 organisms of an isolate cultured from apparently normal pigs caused subclinical infection in 1-day-old piglets after intranasal inoculation. This infection was naturally transmitted between litter mates. Intravenous inoculation of a similar isolate in 7-week-old pigs resulted in a sub-clinical bacteraemia in 3 of 8 piglets. One other piglet developed a bacteraemia 7 days after inoculation and concurrently developed signs of lameness and nervous dysfunction. Ten piglets were inoculated by the subarachnoid route with a porcine isolate and two with an isolate from a person with clinical disease. Only the latter two pigs developed the classical signs of nervous disease associated with infection by<jats:italic>S. suis<\/jats:italic>type 2. It is concluded that strains of<jats:italic>S. suis<\/jats:italic>type 2, of varying pathogenicity for both pigs and man, are endemic in New Zealand. It is suggested that the occurrence of disease is associated with both exposure to a pathogenic strain and other, as yet undetermined, secondary factors.<\/jats:p>","DOI":"10.1017\/s0950268800048081","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:15:03Z","timestamp":1242378903000},"page":"469-478","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["Experimental studies on the comparative infectivity and pathogenicity of<i>Streptococcus suis<\/i>type 2. I. Porcine and human isolates in pigs"],"prefix":"10.1017","volume":"105","author":[{"given":"I. D.","family":"Robertson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. K.","family":"Blackmore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0950268800048081_ref011","unstructured":"11. Clausen HM . Inaugural dissertation, Tierarztliche Hochschule, Hannover, 1980; p. 95. (Abstracted in Vet Bull 1981; 51: 622)."},{"key":"S0950268800048081_ref002","doi-asserted-by":"publisher","DOI":"10.1136\/vr.124.15.391"},{"key":"S0950268800048081_ref003","doi-asserted-by":"publisher","DOI":"10.1136\/vr.107.2.40"},{"key":"S0950268800048081_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3762(83)90005-6"},{"key":"S0950268800048081_ref005","first-page":"171","article-title":"An indirect fluorescent antibody technique for the detection of Streptococcus suis type 2","volume":"39","author":"Robertson","year":"1985","journal-title":"N Z J Med Lab Tech"},{"key":"S0950268800048081_ref008","volume-title":"Veterinary clinical pathology","author":"Coles","year":"1974"},{"key":"S0950268800048081_ref013","unstructured":"13. Robertson ID . PhD thesis, Massey University, Palmerston North, New Zealand 1988."},{"key":"S0950268800048081_ref001","first-page":"290","article-title":"Report of the Veterinary Investigation Service","volume":"105","year":"1979","journal-title":"Vet Record"},{"key":"S0950268800048081_ref006","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.1987.35357"},{"key":"S0950268800048081_ref012","doi-asserted-by":"crossref","first-page":"414","DOI":"10.5694\/j.1326-5377.1983.tb136138.x","article-title":"Streptococcus suis meningitis. An important underdiagnosed disease in Hong Kong","volume":"1","author":"Chau","year":"1983","journal-title":"Med J Aust"},{"key":"S0950268800048081_ref007","doi-asserted-by":"publisher","DOI":"10.2527\/jas1974.395885x"},{"key":"S0950268800048081_ref009","first-page":"8","article-title":"Studies of Streptococcus suis type 2 infection","volume":"8","author":"Clifton-Hadley","year":"1981","journal-title":"Pig Vet Soc Proc"},{"key":"S0950268800048081_ref015","doi-asserted-by":"publisher","DOI":"10.1136\/vr.114.24.584"},{"key":"S0950268800048081_ref004","first-page":"677","article-title":"Streptococcus suis bacteraemia","volume":"100","author":"Dickie","year":"1987","journal-title":"N Z Med J"},{"key":"S0950268800048081_ref010","first-page":"161","article-title":"Infection with RS streptococci in pigs","volume":"89","author":"Pedersen","year":"1981","journal-title":"Acta Path Micro Scand Sect B"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268800048081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T05:07:05Z","timestamp":1589778425000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268800048081\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,12]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1990,12]]}},"alternative-id":["S0950268800048081"],"URL":"https:\/\/doi.org\/10.1017\/s0950268800048081","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,12]]},"assertion":[{"value":"Cambridge University Press 1990","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}