{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T02:13:38Z","timestamp":1648606418272},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":6436,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1991,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A total of 123 drug-resistant and drug-sensitive<jats:italic>Shigella flexneri<\/jats:italic>types 1\u20136, and their<jats:italic>Escherichia coli<\/jats:italic>K12 transconjugants were used for plasmid profile analysis by agarose gel electrophoresis. Resistance factors (R-factors) were further characterized by incompatibility testing.<\/jats:p><jats:p>The overall distribution of small plasmids in<jats:italic>S. flexneri<\/jats:italic>showed that a cryptic plasmid of about 4\u00b76 Kb was found in all serotypes, and a plasmid of about 4\u00b72 Kb was found in serotypes 1\u20134.<jats:italic>Shigella flexneri<\/jats:italic>types 2, 4 and 6 showed a 6\u00b75 Kb plasmid which correlated with SSu-resistance. All<jats:italic>S. flexneri<\/jats:italic>serotypes harboured large plasmids of about 217 Kb. Plasmid profile analysis of<jats:italic>S. flexneri<\/jats:italic>in Ethiopia showed a high degree of uniformity within individual serotypes. However, there was a limited variability which, at times, could be useful for epidemiological investigation.<jats:italic>Shigella flexneri<\/jats:italic>serotypes 1\u20136 harboured resistance plasmids with diverse molecular weights but mostly belonging to incompatibility groups N and X.<\/jats:p>","DOI":"10.1017\/s0950268800048962","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:11:08Z","timestamp":1242378668000},"page":"321-334","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Molecular epidemiology of plasmid patterns in<i>Shigella flexneri<\/i>types 1\u20136"],"prefix":"10.1017","volume":"107","author":[{"given":"A.","family":"Gebre-Yohannes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. 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