{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:11:21Z","timestamp":1715602281789},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":6375,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1991,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The indirect haemagglutination (IHA) test using sensitized turkey erythrocytes and the indirect immunofluorescence assay (IgM-IFA) was confirmed to be sensitive in the detection of a recent or current<jats:italic>Pseudomonas pseudomallei<\/jats:italic>infection in 19 culture-confirmed Singapore melioidosis patients. All were found to have antibody titres from 4 to 32 768 in the IHA test and 10 to 320 in the IgM-IFA test. When these tests were employed on sera from 16 immigrant Thai construction workers who died of sudden unexplained death syndrome (SUDS) and 73 healthy Thai fellow workers, 93\u00b78% and 68\u00b78% of SUDS cases had IHA titre of \u2265 4 and IgM-IFA titre of \u2265 10 respectively, in contrast to 39\u00b77% and 12\u00b73% found among healthy Thai workers. These data indicate that at the time of death, most of the SUDS patients had an active infection with<jats:italic>P. pseudomallei<\/jats:italic>, possibly resulting from reactivation of a latent infection. The aetiological role of<jats:italic>P. pseudomallei<\/jats:italic>as the major cause of SUDS is discussed.<\/jats:p>","DOI":"10.1017\/s095026880004927x","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:09:37Z","timestamp":1242378577000},"page":"577-584","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":7,"title":["Sudden unexplained death syndrome \u2013 a new manifestation in melioidosis?"],"prefix":"10.1017","volume":"107","author":[{"given":"E. H.","family":"Yap","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. C.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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