{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:48:37Z","timestamp":1761630517321},"reference-count":8,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":6375,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1991,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A seroprevalence study was carried out on 1757 outpatients consecutively seen in a sexually transmitted disease (STD) clinic in order to evaluate the sexual transmission of hepatitis C virus (HCV). A total of 1442 consenting patients were tested for hepatitis C, hepatitis B and human immunodeficiency virus type 1 (HCV. HBV, HIV - 1) antibodies. The relations between anti-HCV, anti-HBc and anti-HIV - 1 were studied. Of 73 anti-HCV positive reactions, 45 (61.6%) were confirmed by the recombinant immunoblot assay (RIBA). The proportion of individuals with anti-HCV was higher in outpatients with a history of sexually transmitted disease than without. It was 2.8% in non drug user heterosexuals and 2.9% in non drug user homosexuals. Intravenous drug users (IDU) had higher anti-HCV prevalence when a history of STD was taken into account (42.3% in subjects with STD versus 36.7% in subjects without STD). Among non drug user heterosexuals an association was found between anti-HCV and anti-HBc. These data suggest that sexual transmission of HCV occurs, although it seems to be less efficient than other parenteral modes of transmission. When a more sensitive and specific marker of HCV infection become available, a more accurate estimate of the frequency and efficiency of the sexual transmission will be possible.<\/jats:p>","DOI":"10.1017\/s0950268800049360","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:09:37Z","timestamp":1242378577000},"page":"667-672","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":32,"title":["Heterosexual and homosexual transmission of hepatitis C virus: relation with hepatitis B virus and human immunodeficiency virus type 1"],"prefix":"10.1017","volume":"107","author":[{"given":"R.","family":"Corona","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Prignano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Gentili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Caprilli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Ferrigno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Giglio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Titti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Bruno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Verani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Pasquini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0950268800049360_ref008","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198911303212202"},{"key":"S0950268800049360_ref003","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1989.03430090063034"},{"key":"S0950268800049360_ref001","doi-asserted-by":"publisher","DOI":"10.1126\/science.2523562"},{"key":"S0950268800049360_ref006","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.301.6761.1130"},{"key":"S0950268800049360_ref002","unstructured":"2. Rapicetta M , Rossi GB . Corso di aggiornamento sull'Epatite da HCV. Diagnostica, epidemiologia, prevenzione e terapia. 1990; Rapporti ISTISAN 90\/21."},{"key":"S0950268800049360_ref007","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.301.6745.210"},{"key":"S0950268800049360_ref004","first-page":"23","volume-title":"Proceedings of the International Meeting on Hepatitis B: a sexually transmitted disease in heterosexuals","author":"Pasquini","year":"1990"},{"key":"S0950268800049360_ref005","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450170079026"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268800049360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T19:52:57Z","timestamp":1558122777000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268800049360\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,12]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1991,12]]}},"alternative-id":["S0950268800049360"],"URL":"https:\/\/doi.org\/10.1017\/s0950268800049360","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,12]]},"assertion":[{"value":"Cambridge University Press 1991","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}