{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T20:09:39Z","timestamp":1694635779053},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":6070,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The DNAs of<jats:italic>Shigella sonnei<\/jats:italic>or<jats:italic>Shigella dysenteriae<\/jats:italic>type 1 strains isolated in outbrealis of shigellosis or in sporadic cases were analysed by restriction fragment length polymorphism (RFLP). Southern blots of the DNAs of 36<jats:italic>S. sonnei<\/jats:italic>isolates digested by 8 restriction enzymes were hybridized with an<jats:italic>Escherichia coli<\/jats:italic>rRNA probe. The<jats:italic>S. sonnei<\/jats:italic>strains were unexpectedly diverse in their RFLP. Antibiotypes of the same isolates showed clusters of strains corresponding to the various outbreaks. On the other hand, RFLP analysis suggested concomitant multiple sources of infection rather than a common source and thereby introduced a new insight in the epidemiology of shigellosis. RFLP was also used to trace<jats:italic>S. dysenteriae<\/jats:italic>type 1 transmission in a recent cluster of clinical cases. Although antibiotic resistance patterns indicated the presence of more than one strain, RFLP analysis showed that the six isolates were identical clones and suggested the loss of an R episome after one person-to-person passage.<\/jats:p>","DOI":"10.1017\/s0950268800050226","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:05:30Z","timestamp":1242378330000},"page":"273-282","source":"Crossref","is-referenced-by-count":5,"title":["Molecular epidemiology of shigella infections in Israel"],"prefix":"10.1017","volume":"109","author":[{"given":"M.","family":"Yavzori","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Bercovier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0950268800050226_ref021","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1128\/JCM.29.11.2380-2384.1991","article-title":"Restriction fragment length polymorphisms in rRNA operons for subtyping Shigella sonnei","volume":"29","author":"Hinojosa-Ahumada","year":"1991","journal-title":"J Clin Microbiol"},{"key":"S0950268800050226_ref020","first-page":"1023","volume-title":"Manual of clinical microbiology","author":"Tompkins","year":"1985"},{"key":"S0950268800050226_ref018","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/45.4_ts.493"},{"key":"S0950268800050226_ref016","doi-asserted-by":"crossref","first-page":"10408","DOI":"10.1016\/S0021-9258(19)81531-4","article-title":"Sequencing of the gene ant which affects the Na\/H antiporter activing in Escherichia coli","volume":"263","author":"Karpel","year":"1988","journal-title":"J Biol Chem"},{"key":"S0950268800050226_ref015","first-page":"1.1","volume-title":"Molecular cloning. 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