{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T08:14:22Z","timestamp":1759133662077},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":5401,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1994,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The genomes of 34 recent United Kingdom isolates of<jats:italic>Neisseria meningitidis<\/jats:italic>serogroup C were examined by restriction enzyme digestion and by conventional and pulsed-field gel electrophoresis (PFGE). Strains were assigned to groups on the basis of the Dice similarity coefficient; strains with values of &gt;92% were considered to be clonally related. Twelve clones were identified by PFGE. Strains of two clonal groups predominated. Restriction endonuclease analyses using the \u2018high frequency cleavage\u2019 endonuclease<jats:italic>Stu<\/jats:italic>I and conventional electrophoresis gave 11 groups; in general it had lower resolving power than PFGE.<\/jats:p>","DOI":"10.1017\/s0950268800051463","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T08:48:10Z","timestamp":1242377290000},"page":"53-65","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Molecular epidemiology of recent United Kingdom isolates of<i>Neisseria meningitidis<\/i>serogroup C"],"prefix":"10.1017","volume":"113","author":[{"given":"D. E.","family":"Yakubu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. J. R.","family":"Abadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. H.","family":"Pennington","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0950268800051463_ref033","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1128\/JCM.30.1.132-137.1992","article-title":"Characterization of Neisseria meningitidis serogroup C by multilocus enzyme electrophoresis and ribosomal DNA restriction profiles (ributyping)","volume":"30","author":"Woods","year":"1992","journal-title":"J Clin Microbiol"},{"key":"S0950268800051463_ref026","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/167.6.1320"},{"key":"S0950268800051463_ref022","doi-asserted-by":"publisher","DOI":"10.2307\/1932409"},{"key":"S0950268800051463_ref019","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-38-5-366"},{"key":"S0950268800051463_ref018","doi-asserted-by":"publisher","DOI":"10.1016\/0195-6701(91)90270-I"},{"key":"S0950268800051463_ref010","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0882-4010(88)90047-2","article-title":"Comparison of clonal analysis and DNA restriction analysis for typing of Neisseria meningitidis","volume":"4","author":"Ohyhoek","year":"1988","journal-title":"Microbial Pathogen"},{"key":"S0950268800051463_ref006","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.13.4927"},{"key":"S0950268800051463_ref004","doi-asserted-by":"publisher","DOI":"10.1128\/jb.169.6.2781-2792.1987"},{"key":"S0950268800051463_ref003","unstructured":"3. Fallon RJ . Meningococcal infections in Scotland 1992. Communicable Diseases and Environmental Health in Scotland Weekly Report 1993; 27: 6\u201311."},{"key":"S0950268800051463_ref024","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1993.tb06029.x"},{"key":"S0950268800051463_ref013","doi-asserted-by":"publisher","DOI":"10.1126\/science.3296194"},{"key":"S0950268800051463_ref017","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/161.2.230"},{"key":"S0950268800051463_ref007","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/31.suppl_B.79"},{"key":"S0950268800051463_ref029","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1128\/JCM.29.11.2489-2493.1991","article-title":"Emergence of a virulent clone of Neisseria meningitidis serotype 2a that is associated with meningococcal group C disease in Canada","volume":"29","author":"Ashton","year":"1991","journal-title":"J Clin Microbiol"},{"key":"S0950268800051463_ref031","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1128\/IAI.55.6.1503-1512.1987","article-title":"Genetic relationships and elonal population and elonal population structure of serotype 2 strains of Neisseria meningitidis","volume":"55","author":"Caugant","year":"1987","journal-title":"Infect Immun"},{"key":"S0950268800051463_ref020","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-138-3-523"},{"key":"S0950268800051463_ref032","first-page":"26","volume-title":"Diagnostic molecular microbiology: Principles and applications","author":"Swaminathan","year":"1993"},{"key":"S0950268800051463_ref015","first-page":"5985","article-title":"Restriction endonucleases for pulsed field mapping of bacterial genomes","volume":"197","author":"McClelland","journal-title":"Nucleic Acids Res"},{"key":"S0950268800051463_ref014","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.17.6676"},{"key":"S0950268800051463_ref030","doi-asserted-by":"publisher","DOI":"10.2307\/30147085"},{"key":"S0950268800051463_ref028","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800056508"},{"key":"S0950268800051463_ref016","first-page":"163","volume-title":"The bacterial chromosome","author":"Pattee","year":"1990"},{"key":"S0950268800051463_ref025","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-39-1-3"},{"key":"S0950268800051463_ref002","first-page":"R61","article-title":"Meningococcal infections in England and Wales: 1991","volume":"2","author":"Jones","year":"1992","journal-title":"Commun Dis Rep Rev"},{"key":"S0950268800051463_ref012","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-34-5-265"},{"key":"S0950268800051463_ref011","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800048901"},{"key":"S0950268800051463_ref001","first-page":"R129","article-title":"Meningococcal infections in England and Wales","volume":"3","author":"Jones","year":"1993","journal-title":"Commun Dis Rep Rev"},{"key":"S0950268800051463_ref021","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-765X.1989.tb00262.x"},{"key":"S0950268800051463_ref009","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/9.4.665"},{"key":"S0950268800051463_ref008","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1128\/JCM.19.6.763-765.1984","article-title":"Application of restriction endonuclease fingerprinting of chromosomal DNA of Neisseria meningitidis","volume":"19","author":"Bjorvatn","year":"1984","journal-title":"J Clin Microbiol"},{"key":"S0950268800051463_ref023","volume-title":"The principles and practice of numerical classification","author":"Sneath","year":"1973"},{"key":"S0950268800051463_ref027","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/164.2.368"},{"key":"S0950268800051463_ref005","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.4.867"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268800051463","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T05:04:09Z","timestamp":1589778249000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268800051463\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,8]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1994,8]]}},"alternative-id":["S0950268800051463"],"URL":"https:\/\/doi.org\/10.1017\/s0950268800051463","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,8]]},"assertion":[{"value":"Cambridge University Press 1994","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}