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Sixteen CL wearers with keratitis were compared with 44 asymptomatic controls. Lens hygiene practice was assessed and CL care materials, domestic water sites and endogenous sites were evaluated microbiologically. Poor CL hygiene was not associated with<jats:italic>Ps. aeruginosa<\/jats:italic>keratitis. There was an association between keratitis and bacterial contamination of the CL and storage case (P &lt; 0\u00b70005). Lens and storage case contamination were not significantly associated with poor hygiene. No domestic or endogenous source for<jats:italic>Ps. aeruginosa<\/jats:italic>was found. Causative organisms may be derived from other sources, but CLs and CL storage cases provide a favourable environment for<jats:italic>Ps. aeruginosa<\/jats:italic>colonization. Changing the CL care environment to one less favourable for<jats:italic>Ps. aeruginosa<\/jats:italic>may help to eliminate this problem.<\/jats:p>","DOI":"10.1017\/s0950268800052109","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T08:41:37Z","timestamp":1242376897000},"page":"395-402","source":"Crossref","is-referenced-by-count":87,"title":["Epidemiology of<i>Pseudomonas aeruginosa<\/i>keratitis in contact lens wearers"],"prefix":"10.1017","volume":"114","author":[{"given":"F.","family":"Stapleton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. K. G.","family":"Dart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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