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Approximately 30000 stools from patients with acute diarrhoea were screened for <jats:italic>E. coli<\/jats:italic> O157, and an epidemiological questionnaire filled in for each patient whose stool was positive. Eighty-three patients were studied. The annual incidence was 6 per 100000. Proportionately more infections occurred in people involved in agriculture. Evidence was seen of case-to-case transmission, and contamination of a water supply. Eight cases developed haemolytic uraemic syndrome (HUS). There were 2 deaths due to HUS and 2 due to haemorrhagic colitis (HC). Symptomatic <jats:italic>E. coli<\/jats:italic> infection is relatively common in the Grampian Region, more common in the agricultural community, and is the main cause of HUS in this Region.<\/jats:p>","DOI":"10.1017\/s0950268800052584","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T08:29:05Z","timestamp":1242376145000},"page":"279-284","source":"Crossref","is-referenced-by-count":15,"title":["Epidemiology of infection due to <i>Escherichia coli<\/i> O157: a 3-year prospective study"],"prefix":"10.1017","volume":"116","author":[{"given":"I. A. R.","family":"MacDonald","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I. 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