{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T10:24:53Z","timestamp":1792923893377,"version":"4.5.0"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T00:00:00Z","timestamp":1255910400000},"content-version":"unspecified","delay-in-days":8296,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1987,2]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The study examines the distribution of<jats:italic>Trichuris trichiura<\/jats:italic>infection in a village community in St Lucia, West Indies. The infection intensity of the same age-stratified population was assessed (by drug expelled worm burden and faecal egg count) at the initiation of the study, and after 17 months of reinfection following treatment. The frequency distribution of worm numbers per person was similar at both periods of sampling. There was a significant correlation between the initial infection intensity of an individual, and the intensity acquired by the same individual following the 17 month period of reinfection. This relationship was observed in a broad range of host age classes. The study provides firm evidence that individuals are predisposed to heavy (or light)<jats:italic>T. trichiura<\/jats:italic>infection.<\/jats:p>","DOI":"10.1017\/s0950268800061719","type":"journal-article","created":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T12:48:14Z","timestamp":1255956494000},"page":"65-71","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":69,"title":["Predisposition to<i>Trichuris trichiura<\/i>infection in humans"],"prefix":"10.1017","volume":"98","author":[{"given":"D. A. P.","family":"Bundy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. S.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. E.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Didier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,10,19]]},"reference":[{"key":"S0950268800061719_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)92093-3"},{"key":"S0950268800061719_ref013","unstructured":"Forrester J. E. , Scott M. E. , Bundy D. A. P. & Golden M. H. N. (1986). Familial clustering of Ascaris and Trichuris intense infection in Mexico. American Journal of Tropical Medicine and Hygiene (submitted)."},{"key":"S0950268800061719_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000052288"},{"key":"S0950268800061719_ref020","first-page":"235","article-title":"Trichuris dysentery syndrome","volume":"11","author":"Ramsey","year":"1962","journal-title":"West Indian Medical Journal"},{"key":"S0950268800061719_ref016","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1542\/peds.8.4.548","article-title":"Clinical observation on Trichocephalus trichuris (whipworm) infestation in children","volume":"8","author":"Jung","year":"1951","journal-title":"Pediatrics"},{"key":"S0950268800061719_ref010","volume-title":"Diarrhoea and Malnutrition in Children","author":"Cooper","year":"1986"},{"key":"S0950268800061719_ref017","first-page":"37","article-title":"Present views on the pathogenicity of Trichuris trichiura","volume":"8","author":"Kuori","year":"1952","journal-title":"Revista Cubana de Medicina Tropical"},{"key":"S0950268800061719_ref006","unstructured":"Bundy D. A. P. & Cooper E. S. (1986). The evidence for predisposition to trichuriasis in humans: comparison of institutional and community studies. Annals of Tropical Medicine & Parasitology. (In the Press.)"},{"key":"S0950268800061719_ref023","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-192407000-00009"},{"key":"S0950268800061719_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(86)90367-6"},{"key":"S0950268800061719_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(85)90343-8"},{"key":"S0950268800061719_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60561-8"},{"key":"S0950268800061719_ref002","doi-asserted-by":"publisher","DOI":"10.1038\/297557a0"},{"key":"S0950268800061719_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(86)90369-X"},{"key":"S0950268800061719_ref007","unstructured":"Bundy D. A. P. , Cooper E. S. , Thompson D. E. , Anderson R. M. & Didier-Blanchard J. M. (1986). Age-related changes in the prevalence and intensity of Trichuris trichiura in a St Lucia community. Transactions of the Royal Society of Tropical Medicine and Hygiene. (In the Press.)"},{"key":"S0950268800061719_ref012","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(82)90272-3"},{"key":"S0950268800061719_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(85)90178-6"},{"key":"S0950268800061719_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(83)90103-7"},{"key":"S0950268800061719_ref015","unstructured":"Haswell-Elkins M. R. , Elkins D. B. & Anderson R. M. (1986). The epidemiology and control of intestinal helminths in the Pulicat Lake Region of Southern India. II. Predisposition to heavy or light infection. Transactions of the Royal Society of Tropical Medicine and Hygiene. 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