{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:03:04Z","timestamp":1761058984983},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T00:00:00Z","timestamp":1255910400000},"content-version":"unspecified","delay-in-days":7871,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1988,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A prospective study of faecal colonization with P-fimbriated <jats:italic>Escherichia coli<\/jats:italic> between 0 and 18 months of ago was conducted in 751 healthy infants. The influence of breast-feeding and treatment with antibiotics on this colonization was studied. Colonization with P-fimbriatcd <jats:italic>E. coli<\/jats:italic> increased with age from 10% at 6 days to 30% at 18 months of ago (<jats:italic>P<\/jats:italic> &lt; 0\u00b701). Breast-feeding influenced colonization at 6 weeks of age when breast-fed children harboured fewer bacterial species (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001) and fewer P-fimbriated <jats:italic>E. coli<\/jats:italic> (<jats:italic>P<\/jats:italic> = 0\u00b706) than bottle-fed infants. Treatment with antibiotics increased the colonization rate with P-fimbriatcd <jats:italic>E. coli<\/jats:italic> at the age of 11 months (<jats:italic>P<\/jats:italic> &lt; 0\u00b705). However, this was not true for treatment with ampicillin, which increased colonization rate with Gram-negative species other than <jats:italic>E. coli<\/jats:italic> (<jats:italic>P<\/jats:italic> &lt; 0\u00b705). Fifty per cent (378) of all children were colonized and a quarter (183) had pure cultures of P-fimbriatcd <jats:italic>E. coli<\/jats:italic> in at least one faecal sample. The clinical importance of this colonization remains to be shown.<\/jats:p>","DOI":"10.1017\/s0950268800067315","type":"journal-article","created":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T08:44:01Z","timestamp":1255941841000},"page":"185-191","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":13,"title":["Faecal colonization with P-fimbriated <i>Escherichia coli<\/i> between 0 and 18 months of age"],"prefix":"10.1017","volume":"100","author":[{"given":"K.","family":"Tullus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunilla","family":"K\u00e4llenius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"M\u00f6llby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,10,19]]},"reference":[{"key":"S0950268800067315_ref018","first-page":"1","article-title":"Epidemiology of symtomatic urinary tract infections in childhood","volume":"252","author":"Winberg","year":"1974","journal-title":"Acta Paedialrica Scandinavica"},{"key":"S0950268800067315_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80523-X"},{"key":"S0950268800067315_ref014","doi-asserted-by":"publisher","DOI":"10.1007\/BF01666912"},{"key":"S0950268800067315_ref013","first-page":"25","article-title":"Escherichia coli serotypes in breast-fed and bottlefed infants","volume":"83","author":"\u00d8rskov","year":"1975","journal-title":"Acta Pathologica et Microbiologica Scandinavica"},{"key":"S0950268800067315_ref012","volume-title":"Manual of Clinical Microbiology","author":"Lennette","year":"1980"},{"key":"S0950268800067315_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)92797-5"},{"key":"S0950268800067315_ref015","doi-asserted-by":"publisher","DOI":"10.1007\/BF02013289"},{"key":"S0950268800067315_ref009","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/152.2.426"},{"key":"S0950268800067315_ref016","doi-asserted-by":"publisher","DOI":"10.1007\/BF01646114"},{"key":"S0950268800067315_ref006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1975.tb03928.x"},{"key":"S0950268800067315_ref010","doi-asserted-by":"publisher","DOI":"10.1007\/BF01644802"},{"key":"S0950268800067315_ref017","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105112"},{"key":"S0950268800067315_ref007","first-page":"59","volume-title":"Intensive Care of the Newborn","author":"Graham","year":"1976"},{"key":"S0950268800067315_ref008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1968.tb03490.x"},{"key":"S0950268800067315_ref003","first-page":"210","article-title":"Studies of Escherichia coli O antigen specific antibodies in human milk, maternal serum and cord blood","volume":"65","author":"Carlsson","year":"1976","journal-title":"Ada Paedialrica Scandinavica"},{"key":"S0950268800067315_ref004","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1981.02130260032010"},{"key":"S0950268800067315_ref002","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-198609000-00009"},{"key":"S0950268800067315_ref001","unstructured":"Bennet R. (1987). The fecal microflora of newborn infants during intensive care management, and its relationship to neonatal septicaemia. Thesis. Karolinska Institute."}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268800067315","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T16:05:15Z","timestamp":1558368315000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268800067315\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,4]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1988,4]]}},"alternative-id":["S0950268800067315"],"URL":"https:\/\/doi.org\/10.1017\/s0950268800067315","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,4]]},"assertion":[{"value":"Cambridge University Press 1988","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}