{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T20:02:29Z","timestamp":1778702549039,"version":"3.51.4"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T00:00:00Z","timestamp":1255910400000},"content-version":"unspecified","delay-in-days":5436,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1994,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Enzyme immunoassays (EIA) were used to measure serum antibodies to <jats:italic>Cryptosporidium<\/jats:italic> in four immunocompetent adults with recent proven cryptosporidial infection, 379 healthy children and 73 adult volunteers in Melbourne, Australia, and 205 children in Papua New Guinea (PNG) (47 healthy children; 158 with pneumonia). Antibodies peaked 3\u20136 weeks after infection and fell to baseline within a few months. A high level (5000 EIA units\/ml) or a significant change between paired sera, of IgG or IgM, were taken as evidence of recent infection and found in 24% of PNG children and in 8% of children and 5% of adults in Melbourne. Among PNG children with pneumonia who had high cryptosporidial antibody levels, those with measles (6\/8) were significantly more likely (<jats:italic>P<\/jats:italic> = 0\u00b7002) to have diarrhoea than the remainder (4\/28). Symptomatic cryptosporidiosis may be associated with transient immune suppression due to viral infection. This study indicates that serological surveys can contribute to an understanding of the epidemiology of cryptosporidosis.<\/jats:p>","DOI":"10.1017\/s0950268800068503","type":"journal-article","created":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T08:39:45Z","timestamp":1255941585000},"page":"491-499","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Seroepidemiology of cryptosporidiosis in children in Papua New Guinea and Australia"],"prefix":"10.1017","volume":"113","author":[{"given":"V. J.","family":"Groves","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Lehmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. L.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,10,19]]},"reference":[{"key":"S0950268800068503_ref010","first-page":"125","volume":"14","author":"Dp","year":"1987","journal-title":"The antibody response to Cryptosporidium: development of a serologicial test and its use in a study of immunologically normal persons"},{"key":"S0950268800068503_ref014","first-page":"175","volume":"147","author":"Biggs","year":"1987","journal-title":"Human infection with Cryptosporidium spp.: results of a 24 month survey"},{"key":"S0950268800068503_ref004","first-page":"2436","volume":"55","author":"Bj","year":"1987","journal-title":"Characterization of the Cryptosporidium antigens from sporulated oocysts of Cryptosporidium parvtim"},{"key":"S0950268800068503_ref005","first-page":"422","volume":"48","author":"Ef","year":"1972","journal-title":"Determination of protein: a modification of the Lowry method that gives linear photometric response"},{"key":"S0950268800068503_ref001","first-page":"325","volume":"4","year":"1991","journal-title":"Current WL, Garcia LS. 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