{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T19:34:41Z","timestamp":1772825681019,"version":"3.50.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2002,7,18]],"date-time":"2002-07-18T00:00:00Z","timestamp":1026950400000},"content-version":"unspecified","delay-in-days":47,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2002,6]]},"abstract":"<jats:p>Two enterotoxins, shigella enterotoxin 1 (SHET1) and shigella enterotoxin 2 (SHET2) have been recently characterized and are believed to play a role in the clinical manifestation of shigellosis. One hundred and twenty-one isolates of <jats:italic>Shigella<\/jats:italic> spp. of 13 different serotypes and variants and 10 isolates of enteroinvasive <jats:italic>Escherichia coli<\/jats:italic> (EIEC) isolated in Israel, were examined by polymerase chain reaction for the presence of SHET1 and SHET2 genes. SHET1 was only prevalent among isolates of <jats:italic>S. flexneri<\/jats:italic> 2a while SHET2 was found in all the serotypes that were tested except for several isolates of <jats:italic>S. flexneri<\/jats:italic> 1b that lost their virulence plasmid during storage. In addition, we found that the <jats:italic>S. flexneri<\/jats:italic> 2a vaccine strain T-32 Istrati contains the gene encoding for SHET1 but not that encoding for SHET2, suggesting that the latter is located within a large deletion occurring in the 140\u00a0Mda plasmid of this <jats:italic>S. flexneri<\/jats:italic> 2a non-invasive vaccine strain.<\/jats:p>","DOI":"10.1017\/s0950268802006866","type":"journal-article","created":{"date-parts":[[2002,9,17]],"date-time":"2002-09-17T20:03:38Z","timestamp":1032293018000},"page":"533-535","source":"Crossref","is-referenced-by-count":20,"title":["Prevalence of the genes for shigella enterotoxins 1 and 2 among clinical isolates of shigella in Israel"],"prefix":"10.1017","volume":"128","author":[{"given":"M.","family":"YAVZORI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"COHEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"ORR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2002,7,18]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268802006866","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,5]],"date-time":"2019-04-05T19:01:56Z","timestamp":1554490916000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268802006866\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,6]]}},"alternative-id":["S0950268802006866"],"URL":"https:\/\/doi.org\/10.1017\/s0950268802006866","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,6]]}}}