{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:05:20Z","timestamp":1784120720355,"version":"3.55.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2003,1,10]],"date-time":"2003-01-10T00:00:00Z","timestamp":1042156800000},"content-version":"unspecified","delay-in-days":40,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:p>In March 1999, a large community outbreak of <jats:italic>Escherichia coli<\/jats:italic> O157 infection occurred in North Cumbria. A total of 114 individuals were reported to the Outbreak Control Team (OCT); 88 had laboratory confirmed <jats:italic>E. coli<\/jats:italic> O157. Twenty-eight (32%) of the confirmed cases were admitted to hospital, including three children (3\u00b74%) with haemolytic uraemic syndrome. There were no deaths. A case-control study found that illness was strongly associated with drinking pasteurized milk from a local farm (<jats:italic>P<\/jats:italic>=&lt;0\u00b70001) on single variable analysis. Microbiological investigations at the farm revealed <jats:italic>E. coli<\/jats:italic> O157 phage type (PT) 21\/28 VT 2 which was indistinguishable from the human isolates by pulsed field gel electrophoresis. At the time of occurrence this was the largest <jats:italic>E. coli<\/jats:italic> O157 outbreak in England and Wales and the first <jats:italic>E. coli<\/jats:italic> O157 PT 21\/28 VT 2 outbreak associated with pasteurized milk. This outbreak highlights lessons to be learnt regarding on-farm pasteurization.<\/jats:p>","DOI":"10.1017\/s0950268802007835","type":"journal-article","created":{"date-parts":[[2006,5,10]],"date-time":"2006-05-10T05:43:44Z","timestamp":1147239824000},"page":"451-457","source":"Crossref","is-referenced-by-count":40,"title":["<i>E. coli<\/i> O157 phage type 21\/28 outbreak in North Cumbria associated with pasteurized milk"],"prefix":"10.1017","volume":"129","author":[{"given":"S.","family":"GOH","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"NEWMAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"KNOWLES","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. J.","family":"BOLTON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"HOLLYOAK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"RICHARDS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"DALEY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"COUNTER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. R.","family":"SMITH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"KEPPIE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2003,1,10]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268802007835","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T20:13:08Z","timestamp":1557173588000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268802007835\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["S0950268802007835"],"URL":"https:\/\/doi.org\/10.1017\/s0950268802007835","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,12]]}}}