{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:42:46Z","timestamp":1789684966187,"version":"4.0.1"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2008,1,4]],"date-time":"2008-01-04T00:00:00Z","timestamp":1199404800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2008,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Human rabies in China continues to increase exponentially, largely due to an inadequate veterinary infrastructure and poor vaccine coverage of naive dogs. We performed an epidemiological survey of rabies both in humans and animals, examined vaccine quality for animal use, evaluated the vaccination coverage in dogs, and checked the dog samples for the presence of rabies virus. The lack of surveillance in dog rabies, together with the low immunization coverage (up to 2\u00b78% in rural areas) and the high percentage of rabies virus prevalence (up to 6\u00b74%) in dogs, suggests that the dog population is a continual threat for rabies transmission from dogs to humans in China. Results also indicated that the quality of rabies vaccines for animal use did not satisfy all of the requirements for an efficacious vaccine capable of fully eliminating rabies. These data suggest that the factors noted above are highly correlated with the high incidence of human rabies in China.<\/jats:p>","DOI":"10.1017\/s0950268807000131","type":"journal-article","created":{"date-parts":[[2008,1,4]],"date-time":"2008-01-04T09:33:41Z","timestamp":1199439221000},"page":"1556-1563","source":"Crossref","is-referenced-by-count":59,"title":["Inferior rabies vaccine quality and low immunization coverage in dogs (<i>Canis familiaris<\/i>) in China"],"prefix":"10.1017","volume":"136","author":[{"given":"R.\u00a0L.","family":"HU","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.\u00a0R.","family":"FOOKS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.\u00a0F.","family":"ZHANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"LIU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"ZHANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2008,1,4]]},"reference":[{"key":"S0950268807000131_ref019","first-page":"55","volume-title":"Laboratory Techniques in Rabies","author":"Meslin","year":"1996"},{"key":"S0950268807000131_ref020","unstructured":"20.\u00a0WHO Expert Committee on Biological Standardization. Requirements for rabies vaccine for veterinary use (amendment 1992). Forty-third report. Geneva: World Health Organization, 1994 (WHO Technical Report Series, No. 840), Annex 6."},{"key":"S0950268807000131_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2005.03.006"},{"key":"S0950268807000131_ref012","unstructured":"12.\u00a0 Schneider MC , Epidemiological situation of human rabies in Latin America in 2004. Report from Organizaci\u00f3n Panamericana de la Salud, 2005."},{"key":"S0950268807000131_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1759(97)00212-3"},{"key":"S0950268807000131_ref008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2005.01447.x"},{"key":"S0950268807000131_ref003","doi-asserted-by":"publisher","DOI":"10.3201\/eid1301.060810"},{"key":"S0950268807000131_ref002","doi-asserted-by":"publisher","DOI":"10.2807\/esm.10.11.00574-en"},{"key":"S0950268807000131_ref004","unstructured":"4.\u00a0Ministry of Health of the People's Republic of China. (http:\/\/www.moh.gov.cn)."},{"key":"S0950268807000131_ref001","first-page":"360","article-title":"Re-evaluating the burden of rabies in Asia and Africa","volume":"83","author":"Knobel","year":"2005","journal-title":"Bulletin of World Health Organization"},{"key":"S0950268807000131_ref007","doi-asserted-by":"publisher","DOI":"10.1580\/1080-6032(2001)012[0239:REITC]2.0.CO;2"},{"key":"S0950268807000131_ref018","first-page":"188","volume-title":"OIE Manual of Standards for Diagnostic Tests and Vaccines","author":"Aubert","year":"1996"},{"key":"S0950268807000131_ref006","doi-asserted-by":"publisher","DOI":"10.3201\/eid1001.020774"},{"key":"S0950268807000131_ref014","doi-asserted-by":"publisher","DOI":"10.1177\/014107680209500104"},{"key":"S0950268807000131_ref017","first-page":"493","article-title":"A simple method of estimating fifty per cent end-points","volume":"27","author":"Reed","year":"1938","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"S0950268807000131_ref021","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(91)90188-C"},{"key":"S0950268807000131_ref011","first-page":"213","article-title":"The Pan American Health Organization (PAHO) role in the control of rabies in Latin America","volume":"119","author":"Belotto","year":"2004","journal-title":"Development of Biologicals (Basel)"},{"key":"S0950268807000131_ref005","unstructured":"5.\u00a0World Health Organization. WHO Expert Consultation on Rabies. First Report WHO Technical Report Series, No. 931 2005."},{"key":"S0950268807000131_ref009","doi-asserted-by":"publisher","DOI":"10.3201\/eid1112.040775"},{"key":"S0950268807000131_ref015","first-page":"1","volume-title":"Proceedings of the National Symposium on the Prevention and Control of Zoonoses","year":"2006"},{"key":"S0950268807000131_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2006.04.009"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268807000131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T17:54:03Z","timestamp":1556646843000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268807000131\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,4]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S0950268807000131"],"URL":"https:\/\/doi.org\/10.1017\/s0950268807000131","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,4]]}}}