{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T20:29:49Z","timestamp":1778963389753,"version":"3.51.4"},"reference-count":44,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T00:00:00Z","timestamp":1171843200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Aboriginal Australians in remote communities have high rates of rheumatic heart disease (RHD); yet pharyngitis is reportedly rare whilst pyoderma is common. Some strains of group A streptococci (GAS) have preference for the throat and others for the skin depending on M protein type. A study in three remote communities provided 350 GAS isolates for<jats:italic>emm<\/jats:italic>sequence typing, 244 were also<jats:italic>emm<\/jats:italic>pattern typed. There was 100% correlation between<jats:italic>emm<\/jats:italic>sequence and pattern type. Patterns D and E (non-throat tropic) made up 71% of throat and 87% of skin isolates although patterns A\u2013C (throat tropic) were more common in the throat than the skin (RR 2\u00b73, 95% CI 1\u00b74\u20133\u00b78) whilst the opposite was found for pattern D (RR 2\u00b72, 95% CI 1\u00b77\u20133\u00b70). Pattern E favoured the throat (RR 1\u00b74, 95% CI 1\u00b71\u20131\u00b78). Where environmental factors predispose to skin infection,<jats:italic>emm<\/jats:italic>pattern types D and E prevail, whatever the recovery site.<\/jats:p>","DOI":"10.1017\/s0950268807008023","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T08:49:01Z","timestamp":1171874941000},"page":"1398-1405","source":"Crossref","is-referenced-by-count":33,"title":["Molecular typing of<i>Streptococcus pyogenes<\/i>from remote Aboriginal communities where rheumatic fever is common and pyoderma is the predominant streptococcal infection"],"prefix":"10.1017","volume":"135","author":[{"given":"M.\u00a0I.","family":"McDONALD","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.\u00a0J.","family":"TOWERS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"FAGAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.\u00a0R.","family":"CARAPETIS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.\u00a0J.","family":"CURRIE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,2,19]]},"reference":[{"key":"S0950268807008023_ref042","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a112344"},{"key":"S0950268807008023_ref013","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/120.2.258"},{"key":"S0950268807008023_ref012","first-page":"113","article-title":"Epidemiology of streptococcal infections","volume":"51","author":"Rammelkamp","year":"1955","journal-title":"Harvey Lectures"},{"key":"S0950268807008023_ref038","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80036-5"},{"key":"S0950268807008023_ref025","doi-asserted-by":"publisher","DOI":"10.1086\/315842"},{"key":"S0950268807008023_ref001","first-page":"S144","article-title":"The burden of group A streptococcal pharyngitis in Melbourne families","volume":"119","author":"Danchin","year":"2004","journal-title":"Indian Journal of Medical Research"},{"key":"S0950268807008023_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800003514"},{"key":"S0950268807008023_ref044","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.4.1971-1983.2002"},{"key":"S0950268807008023_ref036","doi-asserted-by":"publisher","DOI":"10.1086\/426443"},{"key":"S0950268807008023_ref033","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/13.10.1335"},{"key":"S0950268807008023_ref022","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1128\/IAI.67.8.3915-3920.1999","article-title":"Selective distribution of a high-affinity plasminogen-binding site among group A streptococci associated with impetigo","volume":"67","author":"Svensson","year":"1999","journal-title":"Infection and Immunity"},{"key":"S0950268807008023_ref037","first-page":"6","article-title":"Outbreak of acute post streptococcal glomerulonephritis in the Northern Territory-2000","volume":"8","author":"Kearns","year":"2001","journal-title":"Northern Territory Disease Control Bulletin"},{"key":"S0950268807008023_ref020","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/173.4.896"},{"key":"S0950268807008023_ref011","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-194104000-00009"},{"key":"S0950268807008023_ref032","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/172.6.1608"},{"key":"S0950268807008023_ref005","unstructured":"5.\u00a0 Brahmadathan KN , Molecular epidemiology of group A streptococcal infections in south Indian children. 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