{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T20:38:13Z","timestamp":1649191093226},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T00:00:00Z","timestamp":1180569600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A collection of 106 <jats:italic>Neisseria gonorrhoeae<\/jats:italic> ciprofloxacin-resistant isolates were typed using <jats:italic>Neisseria gonorrhoeae<\/jats:italic> multi-antigen sequence typing (NG-MAST). Opa-typing was performed on 74 isolates which had non-unique sequence types to determine if further discrimination could be achieved and if so whether this had any epidemiological basis. The 74 isolates were separated into 12 sequence types and 20 opa-types (OT). Seven opa-type clusters were congruent with the sequence types and five sequence types could be subdivided by opa-typing. These results demonstrate that opa-typing can add a further level of discrimination compared with NG-MAST. The surveillance data for isolates in the largest sequence type cluster (ST 147) indicated that two major subdivisions OT 1 and OT 2 differed epidemiologically by patients' sexual preference and geographical location. ST 147 is a common strain that has been isolated in several countries since 1999; our results suggest that it has diverged into at least two epidemiologically discrete forms.<\/jats:p>","DOI":"10.1017\/s0950268807008710","type":"journal-article","created":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T07:40:35Z","timestamp":1180597235000},"page":"417-420","source":"Crossref","is-referenced-by-count":5,"title":["Opa-typing can identify epidemiologically distinct subgroups within <i>Neisseria gonorrhoeae<\/i> multi-antigen sequence type (NG-MAST) clusters"],"prefix":"10.1017","volume":"136","author":[{"given":"A.\u00a0K.","family":"MORRIS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.\u00a0M.","family":"PALMER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"YOUNG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,5,31]]},"reference":[{"key":"S0950268807008710_ref013","unstructured":"13.\u00a0 Trees L , Neisseria gonorrhoeae\u2013multiantigen sequence typing (NG-MAST): An alternative to auxotype\/serotype (A\/S) analysis for gonococcal typing. 16th Biennial meeting of the International Society for Sexually Transmitted Diseases Research, Amsterdam, Netherlands 10\u201313 July 2005 [Abstract WP-024]."},{"key":"S0950268807008710_ref012","unstructured":"12.\u00a0 Hoffman SH , Neisseria gonorrhoeae with increasing ceftriaxone MIC in Denmark 2004: serotyping, bi-locus sequence typing and sexual preference. 16th Biennial meeting of the International Society for Sexually Transmitted Diseases Research, Amsterdam, Netherlands 10\u201313 July 2005 [Abstract WP-035]."},{"key":"S0950268807008710_ref010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1995.mmi_17050865.x"},{"key":"S0950268807008710_ref009","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268801005209"},{"key":"S0950268807008710_ref007","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2004.013565"},{"key":"S0950268807008710_ref008","doi-asserted-by":"publisher","DOI":"10.1007\/BF00155541"},{"key":"S0950268807008710_ref011","doi-asserted-by":"publisher","DOI":"10.1086\/444429"},{"key":"S0950268807008710_ref006","unstructured":"6.\u00a0GRASP Steering Group. The Gonococcal resistance to antimicrobials surveillance programme. Year 2005 report. London: Health Protection Agency, 2006."},{"key":"S0950268807008710_ref005","first-page":"54","article-title":"Gonococcal antibiotic surveillance in Scotland (GASS): prevalence, patterns and trends 2005","volume":"40","author":"Young","year":"2006","journal-title":"Health Protection Scotland"},{"key":"S0950268807008710_ref004","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2006.021733"},{"key":"S0950268807008710_ref003","doi-asserted-by":"publisher","DOI":"10.1097\/01.olq.0000194581.02022.f0"},{"key":"S0950268807008710_ref001","doi-asserted-by":"publisher","DOI":"10.1086\/383047"},{"key":"S0950268807008710_ref002","doi-asserted-by":"publisher","DOI":"10.1097\/01.olq.0000187197.85419.f8"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268807008710","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:28:16Z","timestamp":1556670496000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268807008710\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,31]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S0950268807008710"],"URL":"https:\/\/doi.org\/10.1017\/s0950268807008710","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,31]]}}}