{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:12:24Z","timestamp":1791220344196,"version":"4.1.0"},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T00:00:00Z","timestamp":1282867200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>We report a nosocomial outbreak of Crimean-Congo haemorrhagic fever (CCHF) that affected six patients in June 2009 in Ghaem Hospital, Mashhad, Iran, apparently related to one index case. The last four cases were healthcare workers. Infection was spread by percutaneous exposure to two cases, and probably by direct contact with blood, clothes and sheets, to three others. The diagnosis in the two fatal cases was not confirmed virologically. The diagnosis in four cases who survived was confirmed by specific reverse transcription polymerase chain reaction. The patients were treated with ribavirin. In endemic areas, every patient presenting with a febrile haemorrhagic syndrome should be considered to have a viral haemorrhagic fever until proven otherwise. Patients who meet the criteria for probable CCHF should be admitted to hospital and treated with ribavirin. Appropriate isolation precautions should be immediately initiated.<\/jats:p>","DOI":"10.1017\/s0950268810002001","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T12:47:07Z","timestamp":1282913227000},"page":"862-866","source":"Crossref","is-referenced-by-count":29,"title":["Nosocomial outbreak of Crimean-Congo haemorrhagic fever"],"prefix":"10.1017","volume":"139","author":[{"given":"H. R.","family":"NADERI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. R.","family":"SARVGHAD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"BOJDY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. R.","family":"HADIZADEH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"SADEGHI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"SHEYBANI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,8,27]]},"reference":[{"key":"S0950268810002001_ref007","first-page":"193","article-title":"Clinical manifestations, laboratory findings and clinical outcome in 6 pregnant women with Crimean-Congo hemorrhagic fever","volume":"2","author":"Sharifi Mood","year":"2007","journal-title":"Iranian Journal of Clinical Infectious Diseases"},{"key":"S0950268810002001_ref009","doi-asserted-by":"crossref","first-page":"5","DOI":"10.7883\/yoken.JJID.2009.11","article-title":"Evaluation of the efficacy of ribavirin therapy on survival of Crimean-Congo hemorrhagic fever patients: a case-control study","volume":"62","author":"Izadi","year":"2009","journal-title":"Japanese Journal of Infectious Diseases"},{"key":"S0950268810002001_ref008","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/11.Supplement_4.S794"},{"key":"S0950268810002001_ref006","doi-asserted-by":"crossref","first-page":"494","DOI":"10.7883\/yoken.JJID.2008.494","article-title":"The risk of transmission of Crimean-Congo hemorrhagic fever virus from human cases to first-degree relatives","volume":"61","author":"Izadi","year":"2008","journal-title":"Japanese Journal of Infectious Diseases"},{"key":"S0950268810002001_ref011","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2807\/esm.07.03.00343-en","article-title":"Viral haemorrhagic fevers in Europe-effective control requires a co-ordinated response","volume":"7","author":"Crowcroft","year":"2002","journal-title":"Eurosurveillance"},{"key":"S0950268810002001_ref003","first-page":"204","article-title":"Crimean-Congo hemorrhagic fever","volume":"10","author":"Mardani","year":"2007","journal-title":"Archives of Iranian Medicine"},{"key":"S0950268810002001_ref001","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-6106-6_8"},{"key":"S0950268810002001_ref010","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-6106-6_16"},{"key":"S0950268810002001_ref004","first-page":"475","article-title":"Notice to Readers Update: Management of patients with suspected viral hemorrhagic fever \u2013 United States","volume":"44","year":"1995","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"S0950268810002001_ref005","doi-asserted-by":"crossref","first-page":"443","DOI":"10.4269\/ajtmh.2007.76.443","article-title":"Crimean-Congo hemorrhagic fever among health care workers in Iran","volume":"76","author":"Mardani","year":"2007","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"S0950268810002001_ref012","first-page":"303","volume-title":"Bennett and Brachman's Hospital Infections","author":"Rutala","year":"2007"},{"key":"S0950268810002001_ref002","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-005-4129-x"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268810002001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,3]],"date-time":"2023-06-03T01:20:17Z","timestamp":1685755217000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268810002001\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,27]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0950268810002001"],"URL":"https:\/\/doi.org\/10.1017\/s0950268810002001","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,27]]}}}