{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:49:01Z","timestamp":1790894941089,"version":"4.1.0"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T00:00:00Z","timestamp":1283904000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>In France, haemorrhagic fever with renal syndrome (HFRS) is endemic along the Belgian border. However, this rodent-borne zoonosis caused by the Puumala virus has recently spread south to the Franche-Comt\u00e9 region. We investigated the space\u2013time distribution of HFRS and evaluated the influence of environmental factors that drive the hantavirus reservoir abundance and\/or the disease transmission in this area. A scan test clearly indicated space\u2013time clustering, highlighting a single-year (2005) epidemic in the southern part of the region, preceded by a heat-wave 2 years earlier. A Bayesian regression approach showed an association between a variable reflecting biomass (normalized difference vegetation index) and HFRS incidence. The reasons why HFRS cases recently emerged remain largely unknown, and climate parameters alone do not reliably predict outbreaks. Concerted efforts that combine reservoir monitoring, surveillance, and investigation of human cases are warranted to better understand the epidemiological patterns of HFRS in this area.<\/jats:p>","DOI":"10.1017\/s0950268810002062","type":"journal-article","created":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T07:15:52Z","timestamp":1283930152000},"page":"867-874","source":"Crossref","is-referenced-by-count":25,"title":["Environmental risk factors for haemorrhagic fever with renal syndrome in a French new epidemic area"],"prefix":"10.1017","volume":"139","author":[{"given":"J.-F.","family":"VIEL","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"LEFEBVRE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"MARIANNEAU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"JOLY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"GIRAUDOUX","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"UPEGUI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"TORDO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"HOEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,9,8]]},"reference":[{"key":"S0950268810002062_ref026","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008929526011"},{"key":"S0950268810002062_ref012","doi-asserted-by":"publisher","DOI":"10.1186\/1476-072X-8-1"},{"key":"S0950268810002062_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00774-6"},{"key":"S0950268810002062_ref013","first-page":"385","article-title":"Distribution and kinetics of rodent populations in mid-altitude mountains in agricultural land abandonment","volume":"15","author":"Giraudoux","year":"1994","journal-title":"Acta Oecologica"},{"key":"S0950268810002062_ref027","first-page":"E070503.1","article-title":"Significant increase of hantavirus infections in Germany since the beginning of 2007","volume":"12","author":"Koch","year":"2007","journal-title":"Eurosurveillance"},{"key":"S0950268810002062_ref032","doi-asserted-by":"publisher","DOI":"10.1186\/1476-072X-6-15"},{"key":"S0950268810002062_ref020","unstructured":"20. 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