{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:11:44Z","timestamp":1773922304146,"version":"3.50.1"},"reference-count":39,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T00:00:00Z","timestamp":1302134400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Diversity within<jats:italic>Shigella dysenteriae<\/jats:italic>(<jats:italic>n<\/jats:italic>=40) and<jats:italic>Shigella boydii<\/jats:italic>(<jats:italic>n<\/jats:italic>=30) isolates from children living in Egypt aged &lt;5 years was investigated.<jats:italic>Shigella<\/jats:italic>-associated diarrhoea occurred mainly in summer months and in children aged &lt;3 years, it commonly presented with vomiting and fever. Serotypes 7 (30%), 2 (28%), and 3 (23%) accounted for most of<jats:italic>S. dysenteriae<\/jats:italic>isolates; 50% of<jats:italic>S. boydii<\/jats:italic>isolates were serotype 2.<jats:italic>S. dysenteriae<\/jats:italic>and<jats:italic>S. boydii<\/jats:italic>isolates were often resistant to ampicillin, chloramphenicol and tetracycline (42%, 17%, respectively), although resistance varied among serotypes. Pulsed-field gel electrophoresis separated the isolates into distinct clusters correlating with species and serotype. Genetic differences in trimethoprim\/sulfamethoxazole and \u03b2-lactam-encoding resistance genes were also evident.<jats:italic>S. dysenteriae<\/jats:italic>and<jats:italic>S. boydii<\/jats:italic>are genetically diverse pathogens in Egypt; the high level of multidrug resistance associated with both pathogens and resistance to the most available inexpensive antibiotics underlines the importance of continuing surveillance.<\/jats:p>","DOI":"10.1017\/s0950268811000525","type":"journal-article","created":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T10:58:51Z","timestamp":1302173931000},"page":"299-310","source":"Crossref","is-referenced-by-count":16,"title":["Genetic diversity and antibiotic resistance in<i>Shigella dysenteriae<\/i>and<i>Shigella boydii<\/i>strains isolated from children aged &lt;5 years in Egypt"],"prefix":"10.1017","volume":"140","author":[{"given":"A. 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