{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T05:04:47Z","timestamp":1773983087382,"version":"3.50.1"},"reference-count":36,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T00:00:00Z","timestamp":1326153600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Varicella-zoster virus causes chickenpox (CP) and after reactivation herpes zoster (HZ). Vaccines are available against both diseases warranting an assessment of the pre-vaccination burden of disease. We collected data from relevant Belgian databases and performed five surveys of CP and HZ patients. The rates at which a general practitioner is visited at least once for CP and HZ are 346 and 378\/100 000 person-years, respectively. The average CP and HZ hospitalization rates are 5\u00b73 and 14\u00b72\/100 000 person-years respectively. The direct medical cost for HZ is about twice as large as the direct medical cost for CP. The quality-adjusted life years lost for ambulatory CP patients consulting a physician is more than double that of those not consulting a physician (0\u00b7010<jats:italic>vs<\/jats:italic>. 0\u00b7004). In conclusion, both diseases cause a substantial burden in Belgium.<\/jats:p>","DOI":"10.1017\/s0950268811002640","type":"journal-article","created":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T11:51:17Z","timestamp":1326196277000},"page":"2096-2109","source":"Crossref","is-referenced-by-count":61,"title":["The health and economic burden of chickenpox and herpes zoster in Belgium"],"prefix":"10.1017","volume":"140","author":[{"given":"J.","family":"BILCKE","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"OGUNJIMI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"MARAIS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"DE SMET","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"CALLENS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"CALLAERT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"VAN KERSCHAVER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"RAMET","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"VAN DAMME","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"BEUTELS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,1,10]]},"reference":[{"key":"S0950268811002640_ref030","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.02.004"},{"key":"S0950268811002640_ref027","doi-asserted-by":"publisher","DOI":"10.1086\/512673"},{"key":"S0950268811002640_ref017","unstructured":"17. 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