{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:39:49Z","timestamp":1790253589476,"version":"4.1.0"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2012,5,31]],"date-time":"2012-05-31T00:00:00Z","timestamp":1338422400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Tuberculous meningitis (TBM) is a severe complication of tuberculosis and occurs mainly during early childhood. The incidence rate of TBM varies with season, and serum vitamin D levels, which are dependent on sunlight, might play a role. We studied the association between TBM incidence rate and hours of sunshine in Cape Town, South Africa and found a significant association between the incidence rate of TBM and hours of sunshine 3 months earlier (incidence rate ratio per 100 sunshine hours 0\u00b769, 95% confidence interval 0\u00b754\u20130\u00b788, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7002). The association supports the hypothesis that vitamin D might play a role in the pathophysiology of TBM. Further prospective studies in which vitamin D status is measured are necessary to determine causality.<\/jats:p>","DOI":"10.1017\/s0950268812001045","type":"journal-article","created":{"date-parts":[[2012,5,31]],"date-time":"2012-05-31T08:16:34Z","timestamp":1338452194000},"page":"459-462","source":"Crossref","is-referenced-by-count":16,"title":["Seasonal variation in the incidence rate of tuberculous meningitis is associated with sunshine hours"],"prefix":"10.1017","volume":"141","author":[{"given":"D. H.","family":"VISSER","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. F.","family":"SCHOEMAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. M.","family":"VAN FURTH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2012,5,31]]},"reference":[{"key":"S0950268812001045_ref1","unstructured":"World Health Organization (WHO) Global tuberculosis control: WHO report, 2011 (http:\/\/www.who.int\/tb\/publications\/global_report\/2011\/gtbr11_main.pdf). Accessed 15 April 2012."},{"key":"S0950268812001045_ref8","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2008.062877"},{"key":"S0950268812001045_ref6","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1353"},{"key":"S0950268812001045_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0962-8479(96)90074-X"},{"key":"S0950268812001045_ref4","doi-asserted-by":"publisher","DOI":"10.4103\/0974-777X.77296"},{"key":"S0950268812001045_ref5","doi-asserted-by":"publisher","DOI":"10.3201\/eid1605.091693"},{"key":"S0950268812001045_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.03.004"},{"key":"S0950268812001045_ref9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1111825108"},{"key":"S0950268812001045_ref10","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2008.9984"},{"key":"S0950268812001045_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2008.05.014"},{"key":"S0950268812001045_ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2010.04315.x"},{"key":"S0950268812001045_ref14","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.490380212"},{"key":"S0950268812001045_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2004.08.006"},{"key":"S0950268812001045_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-3879(48)80033-4"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268812001045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T15:32:20Z","timestamp":1556119940000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268812001045\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,31]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S0950268812001045"],"URL":"https:\/\/doi.org\/10.1017\/s0950268812001045","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,31]]}}}