{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T16:23:28Z","timestamp":1788798208007,"version":"build-2803163510"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2012,6,13]],"date-time":"2012-06-13T00:00:00Z","timestamp":1339545600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The Netherlands experienced an unprecedented outbreak of Q fever between 2007 and 2010. The Jeroen Bosch Hospital (JBH) in 's-Hertogenbosch is located in the centre of the epidemic area. Based on Q fever screening programmes, seroprevalence of IgG phase II antibodies to<jats:italic>Coxiella burnetii<\/jats:italic>in the JBH catchment area was 10\u00b77% [785 tested, 84 seropositive, 95% confidence interval (CI) 8\u00b75\u201312\u00b79]. Seroprevalence appeared not to be influenced by age, gender or area of residence. Extrapolating these data, an estimated 40 600 persons (95% CI 32 200\u201348 900) in the JBH catchment area have been infected by<jats:italic>C. burnetii<\/jats:italic>and are, therefore, potentially at risk for chronic Q fever. This figure by far exceeds the nationwide number of notified symptomatic acute Q fever patients and illustrates the magnitude of the Dutch Q fever outbreak. Clinicians in epidemic Q fever areas should be alert for chronic Q fever, even if no acute Q fever is reported.<\/jats:p>","DOI":"10.1017\/s0950268812001203","type":"journal-article","created":{"date-parts":[[2012,6,13]],"date-time":"2012-06-13T10:31:35Z","timestamp":1339583495000},"page":"847-851","source":"Crossref","is-referenced-by-count":71,"title":["Screening for<i>Coxiella burnetii<\/i>seroprevalence in chronic Q fever high-risk groups reveals the magnitude of the Dutch Q fever outbreak"],"prefix":"10.1017","volume":"141","author":[{"given":"L. M.","family":"KAMPSCHREUR","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C. J. P.","family":"HAGENAARS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. C. 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A review of the disease and the results of a serosurvey of humans, cattle, goats and dogs","volume":"83","author":"Kelly","year":"1993","journal-title":"South African Medical Journal"},{"key":"S0950268812001203_ref11","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268811000136"},{"key":"S0950268812001203_ref3","doi-asserted-by":"crossref","DOI":"10.2807\/ese.15.12.19520-en","article-title":"Q fever in the Netherlands: an update on the epidemiology and control measures","volume":"15","author":"van der Hoek","year":"2010","journal-title":"Eurosurveillance"},{"key":"S0950268812001203_ref12","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir234"},{"key":"S0950268812001203_ref14","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2009.09-0168"},{"key":"S0950268812001203_ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410050074010"},{"key":"S0950268812001203_ref10","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00009-11"},{"key":"S0950268812001203_ref2","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1128\/CMR.12.4.518","article-title":"Q fever","volume":"12","author":"Maurin","year":"1999","journal-title":"Clinical Microbiology Reviews"},{"key":"S0950268812001203_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2008.03.002"},{"key":"S0950268812001203_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03250.x"},{"key":"S0950268812001203_ref8","doi-asserted-by":"publisher","DOI":"10.3201\/eid1712.110738"},{"key":"S0950268812001203_ref9","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00454-09"},{"key":"S0950268812001203_ref4","first-page":"180","article-title":"A large outbreak of Q fever in the West Midlands: windborne spread into a metropolitan area?","volume":"1","author":"Hawker","year":"1998","journal-title":"Communicable Diseases and Public Health"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268812001203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T21:17:12Z","timestamp":1642454232000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268812001203\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,13]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0950268812001203"],"URL":"https:\/\/doi.org\/10.1017\/s0950268812001203","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,13]]}}}