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Biochemical characterization and antibiotic susceptibility testing determined that all<jats:italic>S. sonnei<\/jats:italic>isolates were biotype g and multidrug-resistant. Plasmid profiling identified 15 closely related patterns and<jats:italic>Xba<\/jats:italic>I pulsed-field gel electrophoresis confirmed the high degree of genetic similarity between isolates. All<jats:italic>S<\/jats:italic>.<jats:italic>sonnei<\/jats:italic>isolates harboured<jats:italic>ipaH<\/jats:italic>and class II integrase genes and 84\u00b73 and 80% of the MC and BC isolates, respectively carried the<jats:italic>sen<\/jats:italic>gene. Neither the class I integrase nor the<jats:italic>set<\/jats:italic>gene was detected. Our results indicate that<jats:italic>S. sonnei<\/jats:italic>isolates associated with severe diarrhoea were indistinguishable from those associated with mild diarrhoea. Additional genetic tests with greater discrimination might offer an opportunity to determine genetic differences within the globally disseminating biotype g clone.<\/jats:p>","DOI":"10.1017\/s0950268812002002","type":"journal-article","created":{"date-parts":[[2012,9,19]],"date-time":"2012-09-19T08:32:28Z","timestamp":1348043548000},"page":"1614-1624","source":"Crossref","is-referenced-by-count":2,"title":["Comparative analysis of<i>Shigella sonnei<\/i>biotype g isolated from paediatric populations in Egypt, 1999\u20132005"],"prefix":"10.1017","volume":"141","author":[{"given":"J.","family":"DEJLI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"NADA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"MANSOUR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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