{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T11:15:35Z","timestamp":1780658135180,"version":"3.54.1"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2013,3,6]],"date-time":"2013-03-06T00:00:00Z","timestamp":1362528000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A large outbreak of cholera reported during April\u2013July 2009 in the Kendrapada district of Odisha, India was investigated. Forty-one rectal swabs and 41 water samples, collected from diarrhoeal patients and from different villages were bacteriologically analysed for the isolation of bacterial enteriopathogens, antibiogram profile and detection of various toxic genes. The bacteriological analysis of rectal swabs and environmental water samples revealed the presence of <jats:italic>V. cholerae<\/jats:italic> O1 Ogawa biotype El Tor. The <jats:italic>V. cholerae<\/jats:italic> strains were resistant to ciprofloxacin, co-trimoxazole, chloramphenicol, streptomycin, ampicillin, furazolidone and nalidixic acid. The multiplex polymerase chain reaction (PCR) assay on <jats:italic>V. cholerae<\/jats:italic> strains revealed the presence of <jats:italic>ctx<\/jats:italic>A and <jats:italic>tcp<\/jats:italic>A genes. The mismatch amplification of mutation assay (MAMA) PCR on clinical and environmental isolates of <jats:italic>V. cholerae<\/jats:italic> revealed that the strains were El Tor biotype, which harboured the <jats:italic>ctx<\/jats:italic>B gene of the classical strain. The random amplified polymorphic DNA PCR analysis and pulsed-field gel electrophoresis results indicated that the <jats:italic>V. cholerae<\/jats:italic> isolates belonged to the same clone. This investigation gives a warning that the El Tor variant of <jats:italic>V. cholerae<\/jats:italic> has spread to the coastal district causing a large outbreak that requires close monitoring and surveillance on diarrhoeal outbreaks in Odisha.<\/jats:p>","DOI":"10.1017\/s0950268813000368","type":"journal-article","created":{"date-parts":[[2013,3,6]],"date-time":"2013-03-06T09:56:55Z","timestamp":1362563815000},"page":"2560-2567","source":"Crossref","is-referenced-by-count":16,"title":["Large outbreak of cholera caused by El Tor variant <i>Vibrio cholerae<\/i> O1 in the eastern coast of Odisha, India during 2009"],"prefix":"10.1017","volume":"141","author":[{"given":"B. B.","family":"PAL","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. K.","family":"KHUNTIA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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