{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:10:18Z","timestamp":1790518218212,"version":"4.1.0"},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2013,10,7]],"date-time":"2013-10-07T00:00:00Z","timestamp":1381104000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A report on <jats:italic>Toxoplasma gondii<\/jats:italic> by the UK Advisory Committee on the Microbiological Safety of Food recommended that more accurate figures on the burden of disease in the UK are needed. We present the first 5 years of data from an enhanced surveillance scheme for toxoplasmosis in England and Wales. Between 2008 and 2012, 1824 cases were reported, with an average of 365 each year. There were 1109 immunocompetent cases, the majority presenting with lymphadenopathy, and 364 immunosuppressed cases, with central nervous system and systemic symptoms most frequently reported. There were also 190 pregnant and 33 congenital cases. Of the pregnant cases, 148 were asymptomatic (probably detected during screening), while 28 suffered a fetal loss or stillbirth. The enhanced surveillance system has led to an improvement in the detection of toxoplasmosis in England and Wales. However, numbers are still likely to be an underestimate, biasing towards the more severe infections.<\/jats:p>","DOI":"10.1017\/s095026881300246x","type":"journal-article","created":{"date-parts":[[2013,10,7]],"date-time":"2013-10-07T09:35:37Z","timestamp":1381138537000},"page":"1653-1660","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":18,"title":["Enhanced surveillance for toxoplasmosis in England and Wales, 2008\u20132012"],"prefix":"10.1017","volume":"142","author":[{"given":"K.","family":"HALSBY","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"GUY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"SAID","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"FRANCIS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"O'CONNOR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"KIRKBRIDE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"MORGAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2013,10,7]]},"reference":[{"key":"S095026881300246X_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2012.03.029"},{"key":"S095026881300246X_ref12","first-page":"1","article-title":"Scientific opinion of the panel on biological hazards, on a request from EFSA on surveillance and monitoring of Toxoplasma in humans, foods and animals","volume":"583","year":"2007","journal-title":"EFSA Journal"},{"key":"S095026881300246X_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511527005.005"},{"key":"S095026881300246X_ref4","unstructured":"Kemmeren J , Priority setting of foodborne pathogens: disease burden and costs of selected enteric pathogens. RIVM, 2006 (Report 330080001\/2006) (www.rivm.nl\/bibliotheek\/rapporten\/330080001.pdf). Accessed 6 September 2013."},{"key":"S095026881300246X_ref5","unstructured":"Batz M , Hoffmann S , Morris G. Jr. Ranking the risks: the 10 pathogen-food combinations with the greatest burden on public health. University of Florida, Emerging Pathogens Institute, 2011 (http:\/\/www.epi.ufl.edu\/sites\/www.epi.ufl.edu\/files\/RankingTheRisksREPORT.pdf). Accessed 6 September 2013."},{"key":"S095026881300246X_ref6","unstructured":"ACMSF. Risk profile in relation to toxoplasma in the food chain, 2012 (http:\/\/www.food.gov.uk\/multimedia\/pdfs\/committee\/acmsfrtaxopasm.pdf). Accessed 6 September 2013."},{"key":"S095026881300246X_ref1","first-page":"211","article-title":"Toxoplasmosis in the adult","volume":"50","author":"Remington","year":"1974","journal-title":"Bulletin of the New York Academy of Medicine"},{"key":"S095026881300246X_ref11","doi-asserted-by":"publisher","DOI":"10.1177\/096914139600300406"},{"key":"S095026881300246X_ref10","unstructured":"Defra. Zoonoses report UK, 2009. 2011 (http:\/\/www.defra.gov.uk\/publications\/files\/pb13571-zoonoses2009-110125.pdf). Accessed 6 September 2013."},{"key":"S095026881300246X_ref9","unstructured":"Office for National Statistics. Regions (former GORs) (http:\/\/www.ons.gov.uk\/ons\/guide-method\/geography\/beginner-s-guide\/administrative\/england\/government-office-regions\/index.html). Accessed 6 September 2013."},{"key":"S095026881300246X_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70247-5"},{"key":"S095026881300246X_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70303-1"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S095026881300246X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T02:25:21Z","timestamp":1555899921000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S095026881300246X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,7]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S095026881300246X"],"URL":"https:\/\/doi.org\/10.1017\/s095026881300246x","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,7]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2013\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}