{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T13:45:49Z","timestamp":1750686349419},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The population structure of<jats:italic>Staphylococcus aureus<\/jats:italic>is changing globally but the situation regarding dominant clones in sub-Saharan Africa is not clear. We therefore assessed changes in the population structure of clinical<jats:italic>S. aureus<\/jats:italic>isolates obtained in 2007 (<jats:italic>n<\/jats:italic>\u00a0=\u00a075) and 2012 (<jats:italic>n<\/jats:italic>\u00a0=\u00a075) from Northeastern Nigeria. A reduction in resistance to penicillin, gentamicin, erythromycin and clindamycin was observed in 2012. A decrease of methicillin resistance rates (13\u00b73% to 8\u00b70%) was associated with the decline of the ST241 MRSA clone. The proportion of Panton\u2013Valentine leukocidin (PVL)-positive isolates also decreased from 65\u00b73% to 44%, and was linked with the emergence of PVL-negative ST601 clone in 2012. The significant decline in antibiotic resistance in the study area is in contrast to the worldwide trend of increasing resistance rates.<\/jats:p>","DOI":"10.1017\/s0950268813003117","type":"journal-article","created":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T14:40:07Z","timestamp":1386945607000},"page":"1737-1740","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":18,"title":["Population dynamics of<i>Staphylococcus aureus<\/i>from Northeastern Nigeria in 2007 and 2012"],"prefix":"10.1017","volume":"142","author":[{"given":"K. O.","family":"OKON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. O.","family":"SHITTU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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